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Physiological basis of fatigue.

Publication ,  Journal Article
Evans, WJ; Lambert, CP
Published in: Am J Phys Med Rehabil
January 2007

This work summarizes our knowledge of the physiological basis of fatigue and the effects of exercise and pharmacological interventions on fatigue. Fatigue may be defined as physical and/or mental weariness resulting from exertion, that is, an inability to continue exercise at the same intensity with a resultant deterioration in performance. The concept of deconditioning in patients is discussed as well as the implications for their rehabilitation and exercise. Because fatigue may result from a number of causes, including loss of muscle mass, deconditioning, nutritional deficiencies, oxygen delivery, and anemia, it should be treated comprehensively. Antifatigue therapy should be the standard of care for most chronic conditions associated with fatigue.

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Published In

Am J Phys Med Rehabil

DOI

ISSN

0894-9115

Publication Date

January 2007

Volume

86

Issue

1 Suppl

Start / End Page

S29 / S46

Location

United States

Related Subject Headings

  • Research
  • Rehabilitation
  • Physical Exertion
  • Neoplasms
  • Musculoskeletal Physiological Phenomena
  • Multiple Sclerosis
  • Motor Activity
  • Kidney Failure, Chronic
  • Humans
  • Heart Failure
 

Citation

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ICMJE
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Evans, W. J., & Lambert, C. P. (2007). Physiological basis of fatigue. Am J Phys Med Rehabil, 86(1 Suppl), S29–S46. https://doi.org/10.1097/phm.0b013e31802ba53c
Evans, William J., and Charles P. Lambert. “Physiological basis of fatigue.Am J Phys Med Rehabil 86, no. 1 Suppl (January 2007): S29–46. https://doi.org/10.1097/phm.0b013e31802ba53c.
Evans WJ, Lambert CP. Physiological basis of fatigue. Am J Phys Med Rehabil. 2007 Jan;86(1 Suppl):S29–46.
Evans, William J., and Charles P. Lambert. “Physiological basis of fatigue.Am J Phys Med Rehabil, vol. 86, no. 1 Suppl, Jan. 2007, pp. S29–46. Pubmed, doi:10.1097/phm.0b013e31802ba53c.
Evans WJ, Lambert CP. Physiological basis of fatigue. Am J Phys Med Rehabil. 2007 Jan;86(1 Suppl):S29–S46.

Published In

Am J Phys Med Rehabil

DOI

ISSN

0894-9115

Publication Date

January 2007

Volume

86

Issue

1 Suppl

Start / End Page

S29 / S46

Location

United States

Related Subject Headings

  • Research
  • Rehabilitation
  • Physical Exertion
  • Neoplasms
  • Musculoskeletal Physiological Phenomena
  • Multiple Sclerosis
  • Motor Activity
  • Kidney Failure, Chronic
  • Humans
  • Heart Failure