High-speed photoacoustic microscopy of mouse cortical microhemodynamics.
Publication
, Journal Article
Lin, L; Yao, J; Zhang, R; Chen, C-C; Huang, C-H; Li, Y; Wang, L; Chapman, W; Zou, J; Wang, LV
Published in: Journal of biophotonics
June 2017
We applied high-speed photoacoustic microscopy (PAM) for both cortical microenvironment studies and dynamic brain studies, with micrometer-level optical resolution and a millisecond-level cross-sectional imaging speed over a millimeter-level field of view. We monitored blood flow redistribution in mini-stroke mouse models and cerebral autoregulation induced by a vasoactive agent. Our results collectively suggest that high-speed PAM is a promising tool for understanding dynamic neurophysiological phenomena, complementing conventional imaging modalities.
Duke Scholars
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Published In
Journal of biophotonics
DOI
EISSN
1864-0648
ISSN
1864-063X
Publication Date
June 2017
Volume
10
Issue
6-7
Start / End Page
792 / 798
Related Subject Headings
- Spectrum Analysis
- Photoacoustic Techniques
- Optoelectronics & Photonics
- Microscopy
- Mice
- Female
- Brain
- Animals
- 3404 Medicinal and biomolecular chemistry
- 3401 Analytical chemistry
Citation
APA
Chicago
ICMJE
MLA
NLM
Lin, L., Yao, J., Zhang, R., Chen, C.-C., Huang, C.-H., Li, Y., … Wang, L. V. (2017). High-speed photoacoustic microscopy of mouse cortical microhemodynamics. Journal of Biophotonics, 10(6–7), 792–798. https://doi.org/10.1002/jbio.201600236
Lin, Li, Junjie Yao, Ruiying Zhang, Chun-Cheng Chen, Chih-Hsien Huang, Yang Li, Lidai Wang, William Chapman, Jun Zou, and Lihong V. Wang. “High-speed photoacoustic microscopy of mouse cortical microhemodynamics.” Journal of Biophotonics 10, no. 6–7 (June 2017): 792–98. https://doi.org/10.1002/jbio.201600236.
Lin L, Yao J, Zhang R, Chen C-C, Huang C-H, Li Y, et al. High-speed photoacoustic microscopy of mouse cortical microhemodynamics. Journal of biophotonics. 2017 Jun;10(6–7):792–8.
Lin, Li, et al. “High-speed photoacoustic microscopy of mouse cortical microhemodynamics.” Journal of Biophotonics, vol. 10, no. 6–7, June 2017, pp. 792–98. Epmc, doi:10.1002/jbio.201600236.
Lin L, Yao J, Zhang R, Chen C-C, Huang C-H, Li Y, Wang L, Chapman W, Zou J, Wang LV. High-speed photoacoustic microscopy of mouse cortical microhemodynamics. Journal of biophotonics. 2017 Jun;10(6–7):792–798.
Published In
Journal of biophotonics
DOI
EISSN
1864-0648
ISSN
1864-063X
Publication Date
June 2017
Volume
10
Issue
6-7
Start / End Page
792 / 798
Related Subject Headings
- Spectrum Analysis
- Photoacoustic Techniques
- Optoelectronics & Photonics
- Microscopy
- Mice
- Female
- Brain
- Animals
- 3404 Medicinal and biomolecular chemistry
- 3401 Analytical chemistry