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Myopia: Animal Models to Clinical Trials

Statistical analysis of genome-wide association studies for myopia

Publication ,  Chapter
Li, YJ; Fan, Q
January 1, 2010

Genome wide association (GWA) studies have become a powerful approach for identifying genetic loci or susceptibility genes for common complex diseases.While the number of susceptibility loci identified by GWA studies is increasing, GWA studies for myopia are lagging behind many complex diseases. However, it is expected that more GWA studies related to myopia phenotypes will be reported in the near future. In this chapter, we describe the aspects of statistical analysis of the GWA study for myopia, including study design, quality control procedures, methods for association tests, and myopia related analysis issues.

Duke Scholars

DOI

Publication Date

January 1, 2010

Start / End Page

244 / 267
 

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Li, Y. J., & Fan, Q. (2010). Statistical analysis of genome-wide association studies for myopia. In Myopia: Animal Models to Clinical Trials (pp. 244–267). https://doi.org/10.1142/9789812832986_0013
Li, Y. J., and Q. Fan. “Statistical analysis of genome-wide association studies for myopia.” In Myopia: Animal Models to Clinical Trials, 244–67, 2010. https://doi.org/10.1142/9789812832986_0013.
Li YJ, Fan Q. Statistical analysis of genome-wide association studies for myopia. In: Myopia: Animal Models to Clinical Trials. 2010. p. 244–67.
Li, Y. J., and Q. Fan. “Statistical analysis of genome-wide association studies for myopia.” Myopia: Animal Models to Clinical Trials, 2010, pp. 244–67. Scopus, doi:10.1142/9789812832986_0013.
Li YJ, Fan Q. Statistical analysis of genome-wide association studies for myopia. Myopia: Animal Models to Clinical Trials. 2010. p. 244–267.

DOI

Publication Date

January 1, 2010

Start / End Page

244 / 267