
Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats.
Publication
, Journal Article
Singh, Y; Chaudhary, VK; Tyagi, SR; Misra, UK
Published in: Toxicol Lett
February 1984
Rats maintained on a 20% casein diet were given malathion orally throughout the feeding period (100 mg/kg body weight/day, dissolved in groundnut oil). Hepatic choline kinase (EC 2.7.1.32) and cholinephosphate cytidyltransferase (EC 2.7.7.15) activities were inhibited, whereas cholinephosphotransferase (EC 2.7.8.2) activity was not affected by malathion administration. Incorporation of [methyl-14C]L-methionine into hepatic microsomal phosphatidylcholine was significantly reduced by malathion administration.
Duke Scholars
Published In
Toxicol Lett
DOI
ISSN
0378-4274
Publication Date
February 1984
Volume
20
Issue
2
Start / End Page
219 / 223
Location
Netherlands
Related Subject Headings
- Tritium
- Toxicology
- Rats, Inbred Strains
- Rats
- Phosphatidylcholines
- Nucleotidyltransferases
- Microsomes, Liver
- Methionine
- Male
- Malathion
Citation
APA
Chicago
ICMJE
MLA
NLM
Singh, Y., Chaudhary, V. K., Tyagi, S. R., & Misra, U. K. (1984). Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats. Toxicol Lett, 20(2), 219–223. https://doi.org/10.1016/0378-4274(84)90150-4
Singh, Y., V. K. Chaudhary, S. R. Tyagi, and U. K. Misra. “Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats.” Toxicol Lett 20, no. 2 (February 1984): 219–23. https://doi.org/10.1016/0378-4274(84)90150-4.
Singh Y, Chaudhary VK, Tyagi SR, Misra UK. Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats. Toxicol Lett. 1984 Feb;20(2):219–23.
Singh, Y., et al. “Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats.” Toxicol Lett, vol. 20, no. 2, Feb. 1984, pp. 219–23. Pubmed, doi:10.1016/0378-4274(84)90150-4.
Singh Y, Chaudhary VK, Tyagi SR, Misra UK. Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats. Toxicol Lett. 1984 Feb;20(2):219–223.

Published In
Toxicol Lett
DOI
ISSN
0378-4274
Publication Date
February 1984
Volume
20
Issue
2
Start / End Page
219 / 223
Location
Netherlands
Related Subject Headings
- Tritium
- Toxicology
- Rats, Inbred Strains
- Rats
- Phosphatidylcholines
- Nucleotidyltransferases
- Microsomes, Liver
- Methionine
- Male
- Malathion