Skip to main content
Journal cover image

Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats.

Publication ,  Journal Article
Singh, Y; Chaudhary, VK; Tyagi, SR; Misra, UK
Published in: Toxicol Lett
February 1984

Rats maintained on a 20% casein diet were given malathion orally throughout the feeding period (100 mg/kg body weight/day, dissolved in groundnut oil). Hepatic choline kinase (EC 2.7.1.32) and cholinephosphate cytidyltransferase (EC 2.7.7.15) activities were inhibited, whereas cholinephosphotransferase (EC 2.7.8.2) activity was not affected by malathion administration. Incorporation of [methyl-14C]L-methionine into hepatic microsomal phosphatidylcholine was significantly reduced by malathion administration.

Duke Scholars

Published In

Toxicol Lett

DOI

ISSN

0378-4274

Publication Date

February 1984

Volume

20

Issue

2

Start / End Page

219 / 223

Location

Netherlands

Related Subject Headings

  • Tritium
  • Toxicology
  • Rats, Inbred Strains
  • Rats
  • Phosphatidylcholines
  • Nucleotidyltransferases
  • Microsomes, Liver
  • Methionine
  • Male
  • Malathion
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Singh, Y., Chaudhary, V. K., Tyagi, S. R., & Misra, U. K. (1984). Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats. Toxicol Lett, 20(2), 219–223. https://doi.org/10.1016/0378-4274(84)90150-4
Singh, Y., V. K. Chaudhary, S. R. Tyagi, and U. K. Misra. “Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats.Toxicol Lett 20, no. 2 (February 1984): 219–23. https://doi.org/10.1016/0378-4274(84)90150-4.
Singh Y, Chaudhary VK, Tyagi SR, Misra UK. Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats. Toxicol Lett. 1984 Feb;20(2):219–23.
Singh, Y., et al. “Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats.Toxicol Lett, vol. 20, no. 2, Feb. 1984, pp. 219–23. Pubmed, doi:10.1016/0378-4274(84)90150-4.
Singh Y, Chaudhary VK, Tyagi SR, Misra UK. Inhibition of hepatic phosphatidylcholine synthesis by malathion in rats. Toxicol Lett. 1984 Feb;20(2):219–223.
Journal cover image

Published In

Toxicol Lett

DOI

ISSN

0378-4274

Publication Date

February 1984

Volume

20

Issue

2

Start / End Page

219 / 223

Location

Netherlands

Related Subject Headings

  • Tritium
  • Toxicology
  • Rats, Inbred Strains
  • Rats
  • Phosphatidylcholines
  • Nucleotidyltransferases
  • Microsomes, Liver
  • Methionine
  • Male
  • Malathion