Lipogenesis from acetate 1 14C in liver of rats fed millet (Sorghum vulgarie) at different protein levels
Feeding rats defatted millet flour at various protein levels for 6 wk significantly increased their liver total lipids, glycerides, phospholipids, cholesterol and fatty acids. The increase in liver lipids, triglycerides, cholesterol and phospholipids varied with the amounts of dietary protein. In the case of cholesterol, fatty acids, and glycerides, the levels were low at low protein levels, high at intermediate protein levels and again declined with increase in the amount of dietary protein. However, the amounts of liver phospholipids, phosphatidylcholine (PC), and phosphatidyl ethanolamine (PE) were inversely proportional to the amount of millet protein in the diet. Rats fed millet at different protein levels showed an enhanced lipogenesis, cholesterologenesis and enhanced incorporation of acetate 1 14C into liver triglycerides (TG), PC and PE as compared to controls. The effect of feeding millet protein on liver lipids appears to be related to both its quantity and quality.
