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Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein.

Publication ,  Journal Article
Sharma, HS; Misra, UK
Published in: Z Ernahrungswiss
June 1988

The effect of restricted vitamin A supply to the mother on the biochemical development of the heart in rats has been studied. The vitamin A status of female rats was varied by supplying low, medium and adequate amounts (6, 40, 100 micrograms retinol/day/kg body weight respectively) of vitamin A during pregnancy and suckling. The vitamin A status of the mother caused an alteration in the developmental pattern of fetal heart in parameters of tissue weight, DNA, RNA and protein contents and the biosynthesis of DNA and protein from [3H]-thymidine and [3H]-leucine respectively. A dose-dependent effect of vitamin A on the metabolism of DNA, RNA and protein was observed in the developing rat hearts. Hence, emphasis should be given to the adequate availability of vitamin A to dams for the normal growth and development of fetal organs.

Duke Scholars

Published In

Z Ernahrungswiss

DOI

ISSN

0044-264X

Publication Date

June 1988

Volume

27

Issue

2

Start / End Page

119 / 125

Location

Germany

Related Subject Headings

  • Vitamin A Deficiency
  • Vitamin A
  • Rats, Inbred Strains
  • Rats
  • RNA
  • Protein Biosynthesis
  • Pregnancy
  • Nutrition & Dietetics
  • Maternal-Fetal Exchange
  • Heart
 

Citation

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ICMJE
MLA
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Sharma, H. S., & Misra, U. K. (1988). Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein. Z Ernahrungswiss, 27(2), 119–125. https://doi.org/10.1007/BF02021651
Sharma, H. S., and U. K. Misra. “Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein.Z Ernahrungswiss 27, no. 2 (June 1988): 119–25. https://doi.org/10.1007/BF02021651.
Sharma, H. S., and U. K. Misra. “Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein.Z Ernahrungswiss, vol. 27, no. 2, June 1988, pp. 119–25. Pubmed, doi:10.1007/BF02021651.

Published In

Z Ernahrungswiss

DOI

ISSN

0044-264X

Publication Date

June 1988

Volume

27

Issue

2

Start / End Page

119 / 125

Location

Germany

Related Subject Headings

  • Vitamin A Deficiency
  • Vitamin A
  • Rats, Inbred Strains
  • Rats
  • RNA
  • Protein Biosynthesis
  • Pregnancy
  • Nutrition & Dietetics
  • Maternal-Fetal Exchange
  • Heart