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Aging and Decision Making: Empirical and Applied Perspectives

Chapter 2 - Modeling Cost-Benefit Decision Making in Aged Rodents

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Sofia Beas, B; Setlow, B; Samanez-Larkin, GR; Bizon, JL
February 23, 2015

Aging can impact choices between alternatives that differ with respect to relative benefits and "costs" (e.g., time delays or risk); however, much remains to be learned about the specific cognitive, affective, and neural factors that govern choice behavior across the life span. Relative to primates, rodents offer both comparatively short life spans that facilitate longitudinal evaluation of cognition, and enhanced tractability of genetic, cellular, and biochemical approaches important for identifying the neurobiological mechanisms that mediate decision making. This chapter will describe approaches for modeling cost-benefit decision making in aged rodents, with a focus on intertemporal and risky choice. In addition, examples will be provided of how these approaches have yielded convergent findings in animal and human subjects, as well as novel data regarding neurobehavioral mechanisms of age-related alterations in decision making and potential directions for future research.

Duke Scholars

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February 23, 2015

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17 / 40
 

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Sofia Beas, B., Setlow, B., Samanez-Larkin, G. R., & Bizon, J. L. (2015). Chapter 2 - Modeling Cost-Benefit Decision Making in Aged Rodents. In Aging and Decision Making: Empirical and Applied Perspectives (pp. 17–40). https://doi.org/10.1016/B978-0-12-417148-0.00002-9
Sofia Beas, B., B. Setlow, G. R. Samanez-Larkin, and J. L. Bizon. “Chapter 2 - Modeling Cost-Benefit Decision Making in Aged Rodents.” In Aging and Decision Making: Empirical and Applied Perspectives, 17–40, 2015. https://doi.org/10.1016/B978-0-12-417148-0.00002-9.
Sofia Beas B, Setlow B, Samanez-Larkin GR, Bizon JL. Chapter 2 - Modeling Cost-Benefit Decision Making in Aged Rodents. In: Aging and Decision Making: Empirical and Applied Perspectives. 2015. p. 17–40.
Sofia Beas, B., et al. “Chapter 2 - Modeling Cost-Benefit Decision Making in Aged Rodents.” Aging and Decision Making: Empirical and Applied Perspectives, 2015, pp. 17–40. Scopus, doi:10.1016/B978-0-12-417148-0.00002-9.
Sofia Beas B, Setlow B, Samanez-Larkin GR, Bizon JL. Chapter 2 - Modeling Cost-Benefit Decision Making in Aged Rodents. Aging and Decision Making: Empirical and Applied Perspectives. 2015. p. 17–40.

DOI

Publication Date

February 23, 2015

Start / End Page

17 / 40