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Neurogenesis and depression.

Publication ,  Journal Article
Perera, TD; Lisanby, SH
Published in: J Psychiatr Pract
November 2000

The recognition that the brain continues to generate new neurons well into adulthood has made a marked impact on the field of neuroscience in general and specifically on neurobiological models of the pathogenesis of major depression. Stress, neuroendocrine activation, neurotransmitter systems, and other factors can down-regulate the process of neurogenesis and may contribute to certain morphological changes seen in depression. Evidence is emerging that antidepressant treatments may mitigate these effects by stimulating neurogenesis in particular regions of the brain. This review introduces the reader to recent literature on neurogenesis as it relates to the understanding and treatment of depression.

Duke Scholars

Published In

J Psychiatr Pract

DOI

ISSN

1527-4160

Publication Date

November 2000

Volume

6

Issue

6

Start / End Page

322 / 333

Location

United States

Related Subject Headings

  • Psychiatry
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Perera, T. D., & Lisanby, S. H. (2000). Neurogenesis and depression. J Psychiatr Pract, 6(6), 322–333. https://doi.org/10.1097/00131746-200011000-00003

Published In

J Psychiatr Pract

DOI

ISSN

1527-4160

Publication Date

November 2000

Volume

6

Issue

6

Start / End Page

322 / 333

Location

United States

Related Subject Headings

  • Psychiatry
  • 3202 Clinical sciences
  • 1103 Clinical Sciences