Skip to main content
Journal cover image

Correlation between transition percentage of minute volume (TMV%) and outcome of patients with acute respiratory failure.

Publication ,  Journal Article
Peng, C-K; Wu, S-F; Yang, S-H; Hsieh, C-F; Huang, C-C; Huang, Y-CT; Wu, C-P
Published in: J Crit Care
June 2017

PURPOSE: We have previously shown in patients receiving adaptive support ventilation (ASV) that there existed a Transition %MinVol (TMV%) where the patient's work of breathing began to reduce. In this study, we tested the hypothesis that higher TMV% would be associated with poorer outcome in patients with acute respiratory failure. MATERIALS AND METHODS: In this prospective observational study, we recruited patients with acute respiratory failure on ASV between December 2012 and September 2013 in a mixed ICU. The TMV% was determined by adjusting % MinVol until mandatory respiratory frequency was between 0 and 1breath/min. TMV% was measured on the first two days of mechanical ventilation. RESULTS: A total of 337 patients (age: 70±16years) were recruited. In patients whose TMV% increased between Day 1 and Day 2, aOR for mortality was 7.0 (95%CI=2.7-18.3, p<0.001) compared to patients whose TMV% decreased. In patients whose TMV% was unchanged between Day 1 and Day2, aOR for mortality was 3.91 (95%CI=1.80-8.22, p<0.01). CONCLUSIONS: An increase, or lack of decrease, of TMV% from Day 1 to Day 2 was associated with higher risk of in-hospital death.

Duke Scholars

Published In

J Crit Care

DOI

EISSN

1557-8615

Publication Date

June 2017

Volume

39

Start / End Page

178 / 181

Location

United States

Related Subject Headings

  • Ventilator Weaning
  • Tidal Volume
  • Respiratory Insufficiency
  • Respiratory Distress Syndrome
  • Respiration, Artificial
  • Respiration
  • Prospective Studies
  • Middle Aged
  • Male
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Peng, C.-K., Wu, S.-F., Yang, S.-H., Hsieh, C.-F., Huang, C.-C., Huang, Y.-C., & Wu, C.-P. (2017). Correlation between transition percentage of minute volume (TMV%) and outcome of patients with acute respiratory failure. J Crit Care, 39, 178–181. https://doi.org/10.1016/j.jcrc.2017.02.033
Peng, Chung-Kan, Shu-Fen Wu, Shih-Hsing Yang, Chuan-Fa Hsieh, Chung-Chih Huang, Yuh-Chin T. Huang, and Chin-Pyng Wu. “Correlation between transition percentage of minute volume (TMV%) and outcome of patients with acute respiratory failure.J Crit Care 39 (June 2017): 178–81. https://doi.org/10.1016/j.jcrc.2017.02.033.
Peng C-K, Wu S-F, Yang S-H, Hsieh C-F, Huang C-C, Huang Y-CT, et al. Correlation between transition percentage of minute volume (TMV%) and outcome of patients with acute respiratory failure. J Crit Care. 2017 Jun;39:178–81.
Peng, Chung-Kan, et al. “Correlation between transition percentage of minute volume (TMV%) and outcome of patients with acute respiratory failure.J Crit Care, vol. 39, June 2017, pp. 178–81. Pubmed, doi:10.1016/j.jcrc.2017.02.033.
Peng C-K, Wu S-F, Yang S-H, Hsieh C-F, Huang C-C, Huang Y-CT, Wu C-P. Correlation between transition percentage of minute volume (TMV%) and outcome of patients with acute respiratory failure. J Crit Care. 2017 Jun;39:178–181.
Journal cover image

Published In

J Crit Care

DOI

EISSN

1557-8615

Publication Date

June 2017

Volume

39

Start / End Page

178 / 181

Location

United States

Related Subject Headings

  • Ventilator Weaning
  • Tidal Volume
  • Respiratory Insufficiency
  • Respiratory Distress Syndrome
  • Respiration, Artificial
  • Respiration
  • Prospective Studies
  • Middle Aged
  • Male
  • Humans