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Systolic blood pressure goals to reduce cardiovascular disease among older adults.

Publication ,  Journal Article
Muntner, P; Bowling, CB; Shimbo, D
Published in: Am J Med Sci
August 2014

The 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8) was recently published. This guideline recommended that older adults (≥60 years) without diabetes or chronic kidney disease with systolic blood pressure (SBP) ≥150 mm Hg or diastolic blood pressure (DBP) ≥90 mm Hg be initiated on antihypertensive medication with a treatment goal SBP/DBP <150/90 mm Hg. In contrast, the previous 3 JNC guidelines recommended treatment for these individuals be initiated at SBP/DBP ≥140/90 mm Hg with goal SBP/DBP <140/90 mm Hg. In this article, we review randomized trials of antihypertensive medication and observational data on SBP and DBP with cardiovascular outcomes among older adults, possible explanations underlying the different findings from these randomized trials and observational studies, and contemporary antihypertensive treatment patterns among older U.S. adults. In closing, we highlight future research needs related to hypertension and outcomes among older adults.

Duke Scholars

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Published In

Am J Med Sci

DOI

EISSN

1538-2990

Publication Date

August 2014

Volume

348

Issue

2

Start / End Page

129 / 134

Location

United States

Related Subject Headings

  • Systole
  • Randomized Controlled Trials as Topic
  • Practice Guidelines as Topic
  • Middle Aged
  • Humans
  • General & Internal Medicine
  • Evidence-Based Medicine
  • Cardiovascular Diseases
  • Blood Pressure
  • Aged
 

Citation

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Muntner, P., Bowling, C. B., & Shimbo, D. (2014). Systolic blood pressure goals to reduce cardiovascular disease among older adults. Am J Med Sci, 348(2), 129–134. https://doi.org/10.1097/MAJ.0000000000000314
Muntner, Paul, C Barrett Bowling, and Daichi Shimbo. “Systolic blood pressure goals to reduce cardiovascular disease among older adults.Am J Med Sci 348, no. 2 (August 2014): 129–34. https://doi.org/10.1097/MAJ.0000000000000314.
Muntner P, Bowling CB, Shimbo D. Systolic blood pressure goals to reduce cardiovascular disease among older adults. Am J Med Sci. 2014 Aug;348(2):129–34.
Muntner, Paul, et al. “Systolic blood pressure goals to reduce cardiovascular disease among older adults.Am J Med Sci, vol. 348, no. 2, Aug. 2014, pp. 129–34. Pubmed, doi:10.1097/MAJ.0000000000000314.
Muntner P, Bowling CB, Shimbo D. Systolic blood pressure goals to reduce cardiovascular disease among older adults. Am J Med Sci. 2014 Aug;348(2):129–134.
Journal cover image

Published In

Am J Med Sci

DOI

EISSN

1538-2990

Publication Date

August 2014

Volume

348

Issue

2

Start / End Page

129 / 134

Location

United States

Related Subject Headings

  • Systole
  • Randomized Controlled Trials as Topic
  • Practice Guidelines as Topic
  • Middle Aged
  • Humans
  • General & Internal Medicine
  • Evidence-Based Medicine
  • Cardiovascular Diseases
  • Blood Pressure
  • Aged