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Gastric cancer: an infectious disease.

Publication ,  Journal Article
Piazuelo, MB; Epplein, M; Correa, P
Published in: Infect Dis Clin North Am
December 2010

The role of infectious agents and chronic inflammation in carcinogenesis is being increasingly recognized. It has been estimated that about 18% of cancers are directly linked to infections, particularly gastric adenocarcinoma (Helicobacter pylori), cervical carcinoma (human papilloma viruses), and hepatocarcinoma (hepatitis B and C viruses). Multiple clinical trials of COX-2 inhibitors and other antiinflammatory agents have shown a beneficial effect on the development of diverse tumors, such as those of the colon, stomach, prostate, and breast. However, their mechanism of action is not completely understood and may differ among the infectious agents and tumor types. Because gastric adenocarcinomas account for more than 90% of all gastric malignancies, this review focuses on adenocarcinomas.

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Published In

Infect Dis Clin North Am

DOI

EISSN

1557-9824

Publication Date

December 2010

Volume

24

Issue

4

Start / End Page

853 / vii

Location

United States

Related Subject Headings

  • Stomach Neoplasms
  • Microbiology
  • Male
  • Humans
  • Helicobacter pylori
  • Helicobacter Infections
  • Global Health
  • Gastric Mucosa
  • Adenocarcinoma
  • 4202 Epidemiology
 

Citation

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Piazuelo, M. B., Epplein, M., & Correa, P. (2010). Gastric cancer: an infectious disease. Infect Dis Clin North Am, 24(4), 853–vii. https://doi.org/10.1016/j.idc.2010.07.010
Piazuelo, M Blanca, Meira Epplein, and Pelayo Correa. “Gastric cancer: an infectious disease.Infect Dis Clin North Am 24, no. 4 (December 2010): 853–vii. https://doi.org/10.1016/j.idc.2010.07.010.
Piazuelo MB, Epplein M, Correa P. Gastric cancer: an infectious disease. Infect Dis Clin North Am. 2010 Dec;24(4):853–vii.
Piazuelo, M. Blanca, et al. “Gastric cancer: an infectious disease.Infect Dis Clin North Am, vol. 24, no. 4, Dec. 2010, pp. 853–vii. Pubmed, doi:10.1016/j.idc.2010.07.010.
Piazuelo MB, Epplein M, Correa P. Gastric cancer: an infectious disease. Infect Dis Clin North Am. 2010 Dec;24(4):853–vii.
Journal cover image

Published In

Infect Dis Clin North Am

DOI

EISSN

1557-9824

Publication Date

December 2010

Volume

24

Issue

4

Start / End Page

853 / vii

Location

United States

Related Subject Headings

  • Stomach Neoplasms
  • Microbiology
  • Male
  • Humans
  • Helicobacter pylori
  • Helicobacter Infections
  • Global Health
  • Gastric Mucosa
  • Adenocarcinoma
  • 4202 Epidemiology