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Failure of irrigation and débridement for early postoperative periprosthetic infection.

Publication ,  Conference
Fehring, TK; Odum, SM; Berend, KR; Jiranek, WA; Parvizi, J; Bozic, KJ; Della Valle, CJ; Gioe, TJ
Published in: Clin Orthop Relat Res
January 2013

BACKGROUND: Irrigation and débridement (I&D) of periprosthetic infection (PPI) is associated with infection control ranging from 16% to 47%. Mitigating factors include organism type, host factors, and timing of intervention. While the influence of organism type and host factors has been clarified, the timing of intervention remains unclear. QUESTIONS/PURPOSES: We addressed the following questions: What is the failure rate of I&Ds performed within 90 days of primary surgery? And what factors are associated with failure? METHODS: We performed a multicenter retrospective analysis of I&D for PPI within 90 days of primary surgery. We included 86 patients (44 males, 42 females) with an average age of 61 years. Failure was defined as return to the operating room for an infection-related problem. We determined the failure rate of I&D within 90 days of primary surgery and whether the odds of rerevision for infection were associated with Charlson Comorbidity Index, age, sex, joint, organism type, and timing. The minimum followup was 24 months (average, 46 months; range, 24-106 months). RESULTS: 54 of 86 patients (63%) failed. Eight of 10 (80%) failed within the first 10 days, 32 of 57 (56%) within 4 weeks, and 22 of 29 (76%) within 31 to 90 days postoperatively. No covariates were associated with subsequent revision surgery for infection. CONCLUSIONS: I&D for PPI is frequently used in the early postoperative period to control infection. While it is assumed early intervention will lead to control of infection in most cases, our data contradict this assumption.

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Published In

Clin Orthop Relat Res

DOI

EISSN

1528-1132

Publication Date

January 2013

Volume

471

Issue

1

Start / End Page

250 / 257

Location

United States

Related Subject Headings

  • Treatment Failure
  • Therapeutic Irrigation
  • Retrospective Studies
  • Prosthesis-Related Infections
  • Orthopedics
  • Middle Aged
  • Male
  • Knee Prosthesis
  • Infection Control
  • Humans
 

Citation

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Fehring, T. K., Odum, S. M., Berend, K. R., Jiranek, W. A., Parvizi, J., Bozic, K. J., … Gioe, T. J. (2013). Failure of irrigation and débridement for early postoperative periprosthetic infection. In Clin Orthop Relat Res (Vol. 471, pp. 250–257). United States. https://doi.org/10.1007/s11999-012-2373-9
Fehring, Thomas K., Susan M. Odum, Keith R. Berend, William A. Jiranek, Javad Parvizi, Kevin J. Bozic, Craig J. Della Valle, and Terence J. Gioe. “Failure of irrigation and débridement for early postoperative periprosthetic infection.” In Clin Orthop Relat Res, 471:250–57, 2013. https://doi.org/10.1007/s11999-012-2373-9.
Fehring TK, Odum SM, Berend KR, Jiranek WA, Parvizi J, Bozic KJ, et al. Failure of irrigation and débridement for early postoperative periprosthetic infection. In: Clin Orthop Relat Res. 2013. p. 250–7.
Fehring, Thomas K., et al. “Failure of irrigation and débridement for early postoperative periprosthetic infection.Clin Orthop Relat Res, vol. 471, no. 1, 2013, pp. 250–57. Pubmed, doi:10.1007/s11999-012-2373-9.
Fehring TK, Odum SM, Berend KR, Jiranek WA, Parvizi J, Bozic KJ, Della Valle CJ, Gioe TJ. Failure of irrigation and débridement for early postoperative periprosthetic infection. Clin Orthop Relat Res. 2013. p. 250–257.
Journal cover image

Published In

Clin Orthop Relat Res

DOI

EISSN

1528-1132

Publication Date

January 2013

Volume

471

Issue

1

Start / End Page

250 / 257

Location

United States

Related Subject Headings

  • Treatment Failure
  • Therapeutic Irrigation
  • Retrospective Studies
  • Prosthesis-Related Infections
  • Orthopedics
  • Middle Aged
  • Male
  • Knee Prosthesis
  • Infection Control
  • Humans