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HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING THROUGH THE UNDILATED PUPIL IN INFANTS BORN PRETERM OR WITH HYPOXIC INJURY OR HYDROCEPHALUS.

Publication ,  Journal Article
Tran-Viet, D; Wong, BM; Mangalesh, S; Maldonado, R; Cotten, CM; Toth, CA
Published in: Retina
August 2018

PURPOSE: The authors investigated feasibility of undilated handheld spectral domain optical coherence tomography (SDOCT) retinal imaging in preterm infants and children with neurologic abnormalities. METHODS: Under an institutional review board-approved protocol, the authors attempted handheld SDOCT imaging of the retina, choroid, and optic nerve in infants and young children without pupil dilation. Scans were analyzed for quality and successful capture of foveal, optic nerve, and retinal structural parameters and abnormalities. RESULTS: The authors obtained images through an undilated pupil of 11 infants/children over 28 eye imaging sessions, 27 at the bedside without sedation, and one under anesthesia. Infants had retinopathy of prematurity (n = 8), hypoxic ischemic encephalopathy (n = 2), or obstructive hydrocephalus (n = 1 child). Pupil sizes ranged from 1.0 mm to 3.5 mm. The authors captured fovea and optic nerve scans in 25/28 eye imaging sessions, with scans of adequate quality to discern prespecified foveal and optic nerve morphology, and of the 25 sessions, the choroidal-scleral junction was visible in all but 6 sessions. CONCLUSION: Undilated, handheld SDOCT imaging is a potential alternative method to evaluate the retina and optic nerve in patients with relative contraindication to pharmacological pupil dilation. This approach will enable the study of the eye-brain connection and ocular manifestations of neurologic diseases.

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Published In

Retina

DOI

EISSN

1539-2864

Publication Date

August 2018

Volume

38

Issue

8

Start / End Page

1588 / 1594

Location

United States

Related Subject Headings

  • Tomography, Optical Coherence
  • Retinopathy of Prematurity
  • Retina
  • Point-of-Care Systems
  • Pilot Projects
  • Optic Nerve
  • Ophthalmology & Optometry
  • Male
  • Infant, Premature
  • Infant, Newborn
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tran-Viet, D., Wong, B. M., Mangalesh, S., Maldonado, R., Cotten, C. M., & Toth, C. A. (2018). HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING THROUGH THE UNDILATED PUPIL IN INFANTS BORN PRETERM OR WITH HYPOXIC INJURY OR HYDROCEPHALUS. Retina, 38(8), 1588–1594. https://doi.org/10.1097/IAE.0000000000001735
Tran-Viet, Du, Brittany M. Wong, Shwetha Mangalesh, Ramiro Maldonado, C Michael Cotten, and Cynthia A. Toth. “HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING THROUGH THE UNDILATED PUPIL IN INFANTS BORN PRETERM OR WITH HYPOXIC INJURY OR HYDROCEPHALUS.Retina 38, no. 8 (August 2018): 1588–94. https://doi.org/10.1097/IAE.0000000000001735.
Tran-Viet, Du, et al. “HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING THROUGH THE UNDILATED PUPIL IN INFANTS BORN PRETERM OR WITH HYPOXIC INJURY OR HYDROCEPHALUS.Retina, vol. 38, no. 8, Aug. 2018, pp. 1588–94. Pubmed, doi:10.1097/IAE.0000000000001735.
Tran-Viet D, Wong BM, Mangalesh S, Maldonado R, Cotten CM, Toth CA. HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING THROUGH THE UNDILATED PUPIL IN INFANTS BORN PRETERM OR WITH HYPOXIC INJURY OR HYDROCEPHALUS. Retina. 2018 Aug;38(8):1588–1594.

Published In

Retina

DOI

EISSN

1539-2864

Publication Date

August 2018

Volume

38

Issue

8

Start / End Page

1588 / 1594

Location

United States

Related Subject Headings

  • Tomography, Optical Coherence
  • Retinopathy of Prematurity
  • Retina
  • Point-of-Care Systems
  • Pilot Projects
  • Optic Nerve
  • Ophthalmology & Optometry
  • Male
  • Infant, Premature
  • Infant, Newborn