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Do Mixed-Flora Preoperative Urine Cultures Matter?

Publication ,  Journal Article
Polin, MR; Kawasaki, A; Amundsen, CL; Weidner, AC; Siddiqui, NY
Published in: South Med J
June 2017

OBJECTIVES: To determine whether mixed-flora preoperative urine cultures, as compared with no-growth preoperative urine cultures, are associated with a higher prevalence of postoperative urinary tract infections (UTIs). METHODS: This was a retrospective cohort study. Women who underwent urogynecologic surgery were included if their preoperative clean-catch urine culture result was mixed flora or no growth. Women were excluded if they received postoperative antibiotics for reasons other than treatment of a UTI. Women were divided into two cohorts based on preoperative urine culture results-mixed flora or no growth; the prevalence of postoperative UTI was compared between cohorts. Baseline characteristics were compared using χ2 or Student t tests. A logistic regression analysis then was performed. RESULTS: We included 282 women who were predominantly postmenopausal, white, and overweight. There were many concomitant procedures; 46% underwent a midurethral sling procedure and 68% underwent pelvic organ prolapse surgery. Preoperative urine cultures resulted as mixed flora in 192 (68%) and no growth in 90 (32%) patients. Overall, 14% were treated for a UTI postoperatively. There was no difference in the proportion of patients treated for a postoperative UTI between the two cohorts (25 mixed flora vs 13 no growth, P = 0.77). These results remained when controlling for potentially confounding variables in a logistic regression model (adjusted odds ratio 0.92, 95% confidence interval 0.43-1.96). CONCLUSIONS: In women with mixed-flora compared with no-growth preoperative urine cultures, there were no differences in the prevalence of postoperative UTI. The clinical practice of interpreting mixed-flora cultures as negative is appropriate.

Duke Scholars

Published In

South Med J

DOI

EISSN

1541-8243

Publication Date

June 2017

Volume

110

Issue

6

Start / End Page

426 / 429

Location

United States

Related Subject Headings

  • Urine
  • Urinary Tract Infections
  • Urinalysis
  • Suburethral Slings
  • Risk Factors
  • Retrospective Studies
  • Preoperative Period
  • Postoperative Complications
  • Postmenopause
  • Pelvic Organ Prolapse
 

Citation

APA
Chicago
ICMJE
MLA
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Polin, M. R., Kawasaki, A., Amundsen, C. L., Weidner, A. C., & Siddiqui, N. Y. (2017). Do Mixed-Flora Preoperative Urine Cultures Matter? South Med J, 110(6), 426–429. https://doi.org/10.14423/SMJ.0000000000000659
Polin, Michael R., Amie Kawasaki, Cindy L. Amundsen, Alison C. Weidner, and Nazema Y. Siddiqui. “Do Mixed-Flora Preoperative Urine Cultures Matter?South Med J 110, no. 6 (June 2017): 426–29. https://doi.org/10.14423/SMJ.0000000000000659.
Polin MR, Kawasaki A, Amundsen CL, Weidner AC, Siddiqui NY. Do Mixed-Flora Preoperative Urine Cultures Matter? South Med J. 2017 Jun;110(6):426–9.
Polin, Michael R., et al. “Do Mixed-Flora Preoperative Urine Cultures Matter?South Med J, vol. 110, no. 6, June 2017, pp. 426–29. Pubmed, doi:10.14423/SMJ.0000000000000659.
Polin MR, Kawasaki A, Amundsen CL, Weidner AC, Siddiqui NY. Do Mixed-Flora Preoperative Urine Cultures Matter? South Med J. 2017 Jun;110(6):426–429.

Published In

South Med J

DOI

EISSN

1541-8243

Publication Date

June 2017

Volume

110

Issue

6

Start / End Page

426 / 429

Location

United States

Related Subject Headings

  • Urine
  • Urinary Tract Infections
  • Urinalysis
  • Suburethral Slings
  • Risk Factors
  • Retrospective Studies
  • Preoperative Period
  • Postoperative Complications
  • Postmenopause
  • Pelvic Organ Prolapse