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Nanoplasmonic Sensors

Individual plasmonic nanostructures as label free biosensors

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Nusz, G; Chilkoti, A
January 1, 2012

This chapter reviews our work and that of other groups in the use of individual plasmonic nanostructures that are presented by a substrate for the labelfree detection of biomolecular binding events. This class of single particle nanosensors is based on the local surface plasmon resonance (LSPR) behavior of noble metal nanostructures that enables optical transduction of binding events at their surface into an optical signal [1-5]. The LSPR peak location and intensity are sensitive to the local refractive index surrounding the nanoparticle, which is altered by the binding of biomolecular targets to receptor-functionalized nanostructures, and forms the basis of their utility as label-free biosensors.

Duke Scholars

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Publication Date

January 1, 2012

Start / End Page

105 / 126
 

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Nusz, G., & Chilkoti, A. (2012). Individual plasmonic nanostructures as label free biosensors. In Nanoplasmonic Sensors (pp. 105–126). https://doi.org/10.1007/978-1-4614-3933-2_5
Nusz, G., and A. Chilkoti. “Individual plasmonic nanostructures as label free biosensors.” In Nanoplasmonic Sensors, 105–26, 2012. https://doi.org/10.1007/978-1-4614-3933-2_5.
Nusz G, Chilkoti A. Individual plasmonic nanostructures as label free biosensors. In: Nanoplasmonic Sensors. 2012. p. 105–26.
Nusz, G., and A. Chilkoti. “Individual plasmonic nanostructures as label free biosensors.” Nanoplasmonic Sensors, 2012, pp. 105–26. Scopus, doi:10.1007/978-1-4614-3933-2_5.
Nusz G, Chilkoti A. Individual plasmonic nanostructures as label free biosensors. Nanoplasmonic Sensors. 2012. p. 105–126.

DOI

Publication Date

January 1, 2012

Start / End Page

105 / 126