Skip to main content
Journal cover image

Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury.

Publication ,  Journal Article
Lazaridis, C; Yang, M; DeSantis, SM; Luo, ST; Robertson, CS
Published in: J Crit Care
December 2015

OBJECTIVE: The aim of this study was to explore the relationship of intracranial pressure (ICP) with intensive care unit (ICU) length of stay in a large cohort of severe traumatic brain injury patients and identify factors associating with prolonged ICU course. METHODS: This was a single-center database review of de-identified research data that had been prospectively collected; setting: neurosurgical ICU, Ben Taub General Hospital, Houston, TX. RESULTS: In a cohort of 438 severe traumatic brain injury (TBI) patients, 149 (34%) had a motor Glasgow Coma Scale score of 1 to 3 on admission and 284 (65%) had 4 to 5. Intracranial pressure during the ICU course was 19.8±11.2 mm Hg. Favorable outcome was obtained in 148 (34%), and unfavorable, in 211 (48%) patients with a mortality of 28%. ICU length of stay (LOS) was 19.4±13.9 days. Joint modeling of ICP and ICU LOS was undertaken, adjusted for the International Mission for Prognosis and Analysis of Clinical Trials in TBI admission prognostic indicators. A higher ICP was not significantly associated with longer ICU LOS (P=.4). However, presence of a mass lesion on admission head computed tomography was strongly correlated with a prolonged ICU LOS (P=.0007). Diffuse injuries with basal cistern compression or midline shift were marginally associated with a longer ICU LOS (P=.053). CONCLUSIONS: ICP, as monitored and managed according to BTF guidelines, is not associated with ICU length of stay. Patients with severe TBI and a mass lesion on admission head computed tomography were found to have prolonged ICU LOS independently of other indicators of injury severity and intracranial pressure course.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Crit Care

DOI

EISSN

1557-8615

Publication Date

December 2015

Volume

30

Issue

6

Start / End Page

1258 / 1262

Location

United States

Related Subject Headings

  • Young Adult
  • Tomography, X-Ray Computed
  • Texas
  • Risk Factors
  • Prognosis
  • Predictive Value of Tests
  • Monitoring, Physiologic
  • Middle Aged
  • Male
  • Length of Stay
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lazaridis, C., Yang, M., DeSantis, S. M., Luo, S. T., & Robertson, C. S. (2015). Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury. J Crit Care, 30(6), 1258–1262. https://doi.org/10.1016/j.jcrc.2015.08.003
Lazaridis, Christos, Ming Yang, Stacia M. DeSantis, Sheng T. Luo, and Claudia S. Robertson. “Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury.J Crit Care 30, no. 6 (December 2015): 1258–62. https://doi.org/10.1016/j.jcrc.2015.08.003.
Lazaridis C, Yang M, DeSantis SM, Luo ST, Robertson CS. Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury. J Crit Care. 2015 Dec;30(6):1258–62.
Lazaridis, Christos, et al. “Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury.J Crit Care, vol. 30, no. 6, Dec. 2015, pp. 1258–62. Pubmed, doi:10.1016/j.jcrc.2015.08.003.
Lazaridis C, Yang M, DeSantis SM, Luo ST, Robertson CS. Predictors of intensive care unit length of stay and intracranial pressure in severe traumatic brain injury. J Crit Care. 2015 Dec;30(6):1258–1262.
Journal cover image

Published In

J Crit Care

DOI

EISSN

1557-8615

Publication Date

December 2015

Volume

30

Issue

6

Start / End Page

1258 / 1262

Location

United States

Related Subject Headings

  • Young Adult
  • Tomography, X-Ray Computed
  • Texas
  • Risk Factors
  • Prognosis
  • Predictive Value of Tests
  • Monitoring, Physiologic
  • Middle Aged
  • Male
  • Length of Stay