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Acute vincristine neurotoxicity in the presence of hereditary motor and sensory neuropathy type I.

Publication ,  Journal Article
McGuire, SA; Gospe, SM; Dahl, G
Published in: Med Pediatr Oncol
1989

Acute vincristine neurotoxicity leading to a severe motor and sensory neuropathy has been noted in patients with hereditary motor and sensory neuropathy type I (HMSN-I). The case of a 2-year-old boy with acute lymphocytic leukemia and HMSN-I is reported, and additional cases from the literature are reviewed. Severe vincristine neurotoxicity in patients with HMSN-I may be secondary to impairment of both slow and- fast axonal transport. Vincristine should be used with caution in patients with a family history of polyneuropathy.

Duke Scholars

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1989

Volume

17

Issue

6

Start / End Page

520 / 523

Location

United States

Related Subject Headings

  • Vincristine
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Peripheral Nerves
  • Oncology & Carcinogenesis
  • Muscular Atrophy, Spinal
  • Male
  • Humans
  • Child, Preschool
  • Charcot-Marie-Tooth Disease
  • 1114 Paediatrics and Reproductive Medicine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
McGuire, S. A., Gospe, S. M., & Dahl, G. (1989). Acute vincristine neurotoxicity in the presence of hereditary motor and sensory neuropathy type I. Med Pediatr Oncol, 17(6), 520–523. https://doi.org/10.1002/mpo.2950170534
McGuire, S. A., S. M. Gospe, and G. Dahl. “Acute vincristine neurotoxicity in the presence of hereditary motor and sensory neuropathy type I.Med Pediatr Oncol 17, no. 6 (1989): 520–23. https://doi.org/10.1002/mpo.2950170534.
McGuire SA, Gospe SM, Dahl G. Acute vincristine neurotoxicity in the presence of hereditary motor and sensory neuropathy type I. Med Pediatr Oncol. 1989;17(6):520–3.
McGuire, S. A., et al. “Acute vincristine neurotoxicity in the presence of hereditary motor and sensory neuropathy type I.Med Pediatr Oncol, vol. 17, no. 6, 1989, pp. 520–23. Pubmed, doi:10.1002/mpo.2950170534.
McGuire SA, Gospe SM, Dahl G. Acute vincristine neurotoxicity in the presence of hereditary motor and sensory neuropathy type I. Med Pediatr Oncol. 1989;17(6):520–523.

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1989

Volume

17

Issue

6

Start / End Page

520 / 523

Location

United States

Related Subject Headings

  • Vincristine
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Peripheral Nerves
  • Oncology & Carcinogenesis
  • Muscular Atrophy, Spinal
  • Male
  • Humans
  • Child, Preschool
  • Charcot-Marie-Tooth Disease
  • 1114 Paediatrics and Reproductive Medicine