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Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia.

Publication ,  Journal Article
Salerno, SN; Bernhardt, J; Laughon, M; Jhaveri, R; Massaro, M; Gonzalez, D
Published in: J Pediatric Infect Dis Soc
December 3, 2018

We report here the first pharmacokinetic-pharmacodynamic relationship for ceftaroline in a preterm infant born at <28 weeks' gestational age who was given ceftaroline (8.5 mg/kg every 8 hours) for pneumonia attributable to methicillin-resistant Staphyloccocus aureus. This dose of ceftaroline was adequate to achieve the pharmacodynamic endpoint associated with efficacy for methicillin-resistant Staphyloccocus aureus.

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Published In

J Pediatric Infect Dis Soc

DOI

EISSN

2048-7207

Publication Date

December 3, 2018

Volume

7

Issue

4

Start / End Page

342 / 345

Location

England

Related Subject Headings

  • Rifampin
  • Pneumonia, Staphylococcal
  • Methicillin-Resistant Staphylococcus aureus
  • Infant, Premature, Diseases
  • Infant, Premature
  • Infant, Newborn
  • Humans
  • Female
  • Fatal Outcome
  • Drug Therapy, Combination
 

Citation

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Salerno, S. N., Bernhardt, J., Laughon, M., Jhaveri, R., Massaro, M., & Gonzalez, D. (2018). Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia. J Pediatric Infect Dis Soc, 7(4), 342–345. https://doi.org/10.1093/jpids/pix084
Salerno, Sara N., Janice Bernhardt, Matthew Laughon, Ravi Jhaveri, Matthew Massaro, and Daniel Gonzalez. “Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia.J Pediatric Infect Dis Soc 7, no. 4 (December 3, 2018): 342–45. https://doi.org/10.1093/jpids/pix084.
Salerno SN, Bernhardt J, Laughon M, Jhaveri R, Massaro M, Gonzalez D. Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia. J Pediatric Infect Dis Soc. 2018 Dec 3;7(4):342–5.
Salerno, Sara N., et al. “Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia.J Pediatric Infect Dis Soc, vol. 7, no. 4, Dec. 2018, pp. 342–45. Pubmed, doi:10.1093/jpids/pix084.
Salerno SN, Bernhardt J, Laughon M, Jhaveri R, Massaro M, Gonzalez D. Pharmacokinetics of Ceftaroline in a Preterm Infant With Methicillin-Resistant Staphylococcus Aureus Pneumonia. J Pediatric Infect Dis Soc. 2018 Dec 3;7(4):342–345.
Journal cover image

Published In

J Pediatric Infect Dis Soc

DOI

EISSN

2048-7207

Publication Date

December 3, 2018

Volume

7

Issue

4

Start / End Page

342 / 345

Location

England

Related Subject Headings

  • Rifampin
  • Pneumonia, Staphylococcal
  • Methicillin-Resistant Staphylococcus aureus
  • Infant, Premature, Diseases
  • Infant, Premature
  • Infant, Newborn
  • Humans
  • Female
  • Fatal Outcome
  • Drug Therapy, Combination