
Metal-binding hydrazone photoswitches for visible light reactivity and variable relaxation kinetics.
The range of applications for photoswitching moieties is diverse, and the ability to design switches with variable photochemical and physical properties is consequently important for realizing their potential. Previously we reported on the photochromism of (E)-N'-(1-(2-hydroxyphenyl)ethylidene)isonicotinohydrazide (HAPI), an aroylhydrazone compound first developed as a transition metal chelator. Herein we report the synthesis of structurally related aroylhydrazone chelators and explore the effect of these modifications on their UVA, UVC and blue light photoreactivity, photostationary state composition, photoisomer thermal stability, and relative iron(iii) binding affinity. These findings will inform the next generation of aroylhydrazone photoswitches for metal-gated photoswitching applications.
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- Organic Chemistry
- 4004 Chemical engineering
- 3406 Physical chemistry
- 0601 Biochemistry and Cell Biology
- 0306 Physical Chemistry (incl. Structural)
- 0299 Other Physical Sciences
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Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Organic Chemistry
- 4004 Chemical engineering
- 3406 Physical chemistry
- 0601 Biochemistry and Cell Biology
- 0306 Physical Chemistry (incl. Structural)
- 0299 Other Physical Sciences