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Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications?

Publication ,  Journal Article
Villeneuve, C; Kou, HH; Eckermann, H; Palkar, A; Anderson, LG; McKenney, EA; Bollinger, RR; Parker, W
Published in: Microbes Infect
March 2018

For thousands of years, changes in human cultures have altered the biota associated with the human body, and those alterations have strongly influenced human health. The hygiene hypothesis has evolved over the past 30 years into a nuanced biota alteration theory, but modern medical priorities and regulatory policies have resulted in tragic underutilization of the acquired knowledge.

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Published In

Microbes Infect

DOI

EISSN

1769-714X

Publication Date

March 2018

Volume

20

Issue

3

Start / End Page

147 / 155

Location

France

Related Subject Headings

  • Public Health
  • Models, Biological
  • Microbiota
  • Microbiology
  • Inflammation
  • Hygiene Hypothesis
  • Humans
  • Host-Pathogen Interactions
  • Culture
  • Biota
 

Citation

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ICMJE
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Villeneuve, C., Kou, H. H., Eckermann, H., Palkar, A., Anderson, L. G., McKenney, E. A., … Parker, W. (2018). Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications? Microbes Infect, 20(3), 147–155. https://doi.org/10.1016/j.micinf.2017.11.001
Villeneuve, Chantal, Henry H. Kou, Henrik Eckermann, Antara Palkar, Lauren G. Anderson, Erin A. McKenney, R Randal Bollinger, and William Parker. “Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications?Microbes Infect 20, no. 3 (March 2018): 147–55. https://doi.org/10.1016/j.micinf.2017.11.001.
Villeneuve C, Kou HH, Eckermann H, Palkar A, Anderson LG, McKenney EA, et al. Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications? Microbes Infect. 2018 Mar;20(3):147–55.
Villeneuve, Chantal, et al. “Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications?Microbes Infect, vol. 20, no. 3, Mar. 2018, pp. 147–55. Pubmed, doi:10.1016/j.micinf.2017.11.001.
Villeneuve C, Kou HH, Eckermann H, Palkar A, Anderson LG, McKenney EA, Bollinger RR, Parker W. Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications? Microbes Infect. 2018 Mar;20(3):147–155.
Journal cover image

Published In

Microbes Infect

DOI

EISSN

1769-714X

Publication Date

March 2018

Volume

20

Issue

3

Start / End Page

147 / 155

Location

France

Related Subject Headings

  • Public Health
  • Models, Biological
  • Microbiota
  • Microbiology
  • Inflammation
  • Hygiene Hypothesis
  • Humans
  • Host-Pathogen Interactions
  • Culture
  • Biota