
Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications?
Publication
, Journal Article
Villeneuve, C; Kou, HH; Eckermann, H; Palkar, A; Anderson, LG; McKenney, EA; Bollinger, RR; Parker, W
Published in: Microbes Infect
March 2018
For thousands of years, changes in human cultures have altered the biota associated with the human body, and those alterations have strongly influenced human health. The hygiene hypothesis has evolved over the past 30 years into a nuanced biota alteration theory, but modern medical priorities and regulatory policies have resulted in tragic underutilization of the acquired knowledge.
Duke Scholars
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Published In
Microbes Infect
DOI
EISSN
1769-714X
Publication Date
March 2018
Volume
20
Issue
3
Start / End Page
147 / 155
Location
France
Related Subject Headings
- Public Health
- Models, Biological
- Microbiota
- Microbiology
- Inflammation
- Hygiene Hypothesis
- Humans
- Host-Pathogen Interactions
- Culture
- Biota
Citation
APA
Chicago
ICMJE
MLA
NLM
Villeneuve, C., Kou, H. H., Eckermann, H., Palkar, A., Anderson, L. G., McKenney, E. A., … Parker, W. (2018). Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications? Microbes Infect, 20(3), 147–155. https://doi.org/10.1016/j.micinf.2017.11.001
Villeneuve, Chantal, Henry H. Kou, Henrik Eckermann, Antara Palkar, Lauren G. Anderson, Erin A. McKenney, R Randal Bollinger, and William Parker. “Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications?” Microbes Infect 20, no. 3 (March 2018): 147–55. https://doi.org/10.1016/j.micinf.2017.11.001.
Villeneuve C, Kou HH, Eckermann H, Palkar A, Anderson LG, McKenney EA, et al. Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications? Microbes Infect. 2018 Mar;20(3):147–55.
Villeneuve, Chantal, et al. “Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications?” Microbes Infect, vol. 20, no. 3, Mar. 2018, pp. 147–55. Pubmed, doi:10.1016/j.micinf.2017.11.001.
Villeneuve C, Kou HH, Eckermann H, Palkar A, Anderson LG, McKenney EA, Bollinger RR, Parker W. Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications? Microbes Infect. 2018 Mar;20(3):147–155.

Published In
Microbes Infect
DOI
EISSN
1769-714X
Publication Date
March 2018
Volume
20
Issue
3
Start / End Page
147 / 155
Location
France
Related Subject Headings
- Public Health
- Models, Biological
- Microbiota
- Microbiology
- Inflammation
- Hygiene Hypothesis
- Humans
- Host-Pathogen Interactions
- Culture
- Biota