Justicidin E: A new leukotriene biosynthesis inhibitor.
Publication
, Journal Article
Thérien, M; Fitzsimmons, BJ; Scheigets, J; Macdonald, D; Choo, LY; Guay, J; Falgueyret, JP; Riendeau, D
Published in: Bioorganic and Medicinal Chemistry Letters
January 1, 1993
Justicidin E, an arylnaphthalene lignan, has been identified as a potent inhibitor of leukotriene biosynthesis by human leukocytes (IC50 = 70 nM) and a non-redox inhibitor of 5-lipoxygenase activity. © 1993.
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Published In
Bioorganic and Medicinal Chemistry Letters
DOI
ISSN
0960-894X
Publication Date
January 1, 1993
Volume
3
Issue
10
Start / End Page
2063 / 2066
Related Subject Headings
- Medicinal & Biomolecular Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 1115 Pharmacology and Pharmaceutical Sciences
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry
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Thérien, M., Fitzsimmons, B. J., Scheigets, J., Macdonald, D., Choo, L. Y., Guay, J., … Riendeau, D. (1993). Justicidin E: A new leukotriene biosynthesis inhibitor. Bioorganic and Medicinal Chemistry Letters, 3(10), 2063–2066. https://doi.org/10.1016/S0960-894X(01)81016-7
Thérien, M., B. J. Fitzsimmons, J. Scheigets, D. Macdonald, L. Y. Choo, J. Guay, J. P. Falgueyret, and D. Riendeau. “Justicidin E: A new leukotriene biosynthesis inhibitor.” Bioorganic and Medicinal Chemistry Letters 3, no. 10 (January 1, 1993): 2063–66. https://doi.org/10.1016/S0960-894X(01)81016-7.
Thérien M, Fitzsimmons BJ, Scheigets J, Macdonald D, Choo LY, Guay J, et al. Justicidin E: A new leukotriene biosynthesis inhibitor. Bioorganic and Medicinal Chemistry Letters. 1993 Jan 1;3(10):2063–6.
Thérien, M., et al. “Justicidin E: A new leukotriene biosynthesis inhibitor.” Bioorganic and Medicinal Chemistry Letters, vol. 3, no. 10, Jan. 1993, pp. 2063–66. Scopus, doi:10.1016/S0960-894X(01)81016-7.
Thérien M, Fitzsimmons BJ, Scheigets J, Macdonald D, Choo LY, Guay J, Falgueyret JP, Riendeau D. Justicidin E: A new leukotriene biosynthesis inhibitor. Bioorganic and Medicinal Chemistry Letters. 1993 Jan 1;3(10):2063–2066.
Published In
Bioorganic and Medicinal Chemistry Letters
DOI
ISSN
0960-894X
Publication Date
January 1, 1993
Volume
3
Issue
10
Start / End Page
2063 / 2066
Related Subject Headings
- Medicinal & Biomolecular Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 1115 Pharmacology and Pharmaceutical Sciences
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry