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Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme.

Publication ,  Journal Article
Thérien, M; Skorey, K; Zamboni, R; Li, CS; Lau, CK; LeRiche, T; Linh Truong, V; Waddleton, D; Ramachandran, C
Published in: Bioorganic & medicinal chemistry letters
May 2004

The synthesis of a novel radioactive peptidic photoaffinity probe for the PTP-1B enzyme as well as some SAR leading to the choice of this compound as a photoaffinity probe are presented.

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Published In

Bioorganic & medicinal chemistry letters

DOI

EISSN

1464-3405

ISSN

0960-894X

Publication Date

May 2004

Volume

14

Issue

9

Start / End Page

2319 / 2322

Related Subject Headings

  • Protein Tyrosine Phosphatases
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1
  • Photoaffinity Labels
  • Medicinal & Biomolecular Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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Thérien, M., Skorey, K., Zamboni, R., Li, C. S., Lau, C. K., LeRiche, T., … Ramachandran, C. (2004). Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme. Bioorganic & Medicinal Chemistry Letters, 14(9), 2319–2322. https://doi.org/10.1016/j.bmcl.2004.01.101
Thérien, Michel, Kathryn Skorey, Robert Zamboni, Chun Sing Li, Cheuk K. Lau, Tammy LeRiche, Vouy Linh Truong, Deena Waddleton, and Chidambaram Ramachandran. “Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme.Bioorganic & Medicinal Chemistry Letters 14, no. 9 (May 2004): 2319–22. https://doi.org/10.1016/j.bmcl.2004.01.101.
Thérien M, Skorey K, Zamboni R, Li CS, Lau CK, LeRiche T, et al. Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme. Bioorganic & medicinal chemistry letters. 2004 May;14(9):2319–22.
Thérien, Michel, et al. “Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme.Bioorganic & Medicinal Chemistry Letters, vol. 14, no. 9, May 2004, pp. 2319–22. Epmc, doi:10.1016/j.bmcl.2004.01.101.
Thérien M, Skorey K, Zamboni R, Li CS, Lau CK, LeRiche T, Linh Truong V, Waddleton D, Ramachandran C. Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme. Bioorganic & medicinal chemistry letters. 2004 May;14(9):2319–2322.
Journal cover image

Published In

Bioorganic & medicinal chemistry letters

DOI

EISSN

1464-3405

ISSN

0960-894X

Publication Date

May 2004

Volume

14

Issue

9

Start / End Page

2319 / 2322

Related Subject Headings

  • Protein Tyrosine Phosphatases
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1
  • Photoaffinity Labels
  • Medicinal & Biomolecular Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry