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Association of APOE and other genetic polymorphisms with prospective concussion risk in a prospective cohort study of college athletes

Publication ,  Conference
Terrell, TR; Bostick, R; Rogers, GL; Langston, MA; Barth, J; Bennett, E; Sloane, R; Galloway, L; Cantu, RC; Mihelic, FM
Published in: Proceedings of the 2014 Biomedical Sciences and Engineering Conference 5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014
July 29, 2014

The management of sports concussion and an understanding of its risk factors are major foci i. The literature on athletic injury. Althoug. There is known influence of some genetic polymorphisms (GPs), such as APOE an. The APOE promoter, on traumatic brain injury (TBI) outcome in non-athletic populations, very little work has focused o. The rol. These GPs may play in sports concussion. We completed a large (n=3274) multi-center prospective cohort study of college athletes to study possible associations between various GPs and prospectively occurring sports concussion. We found no significant relationship betwee. The APOE e4 allele. The APOE G-219T promoter. The tau exon 6 Ser53pro o. The tau His47Tyr GPs on prospective concussion. Additional study of other GPs and haplotype combinations is a next logical step i. The search for genetic predisposition to sports-related concussion.

Duke Scholars

Published In

Proceedings of the 2014 Biomedical Sciences and Engineering Conference 5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014

DOI

ISBN

9781479941599

Publication Date

July 29, 2014
 

Citation

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Terrell, T. R., Bostick, R., Rogers, G. L., Langston, M. A., Barth, J., Bennett, E., … Mihelic, F. M. (2014). Association of APOE and other genetic polymorphisms with prospective concussion risk in a prospective cohort study of college athletes. In Proceedings of the 2014 Biomedical Sciences and Engineering Conference  5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations  the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014. https://doi.org/10.1109/BSEC.2014.6867745
Terrell, T. R., R. Bostick, G. L. Rogers, M. A. Langston, J. Barth, E. Bennett, R. Sloane, L. Galloway, R. C. Cantu, and F. M. Mihelic. “Association of APOE and other genetic polymorphisms with prospective concussion risk in a prospective cohort study of college athletes.” In Proceedings of the 2014 Biomedical Sciences and Engineering Conference  5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations  the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014, 2014. https://doi.org/10.1109/BSEC.2014.6867745.
Terrell TR, Bostick R, Rogers GL, Langston MA, Barth J, Bennett E, et al. Association of APOE and other genetic polymorphisms with prospective concussion risk in a prospective cohort study of college athletes. In: Proceedings of the 2014 Biomedical Sciences and Engineering Conference  5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations  the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014. 2014.
Terrell, T. R., et al. “Association of APOE and other genetic polymorphisms with prospective concussion risk in a prospective cohort study of college athletes.” Proceedings of the 2014 Biomedical Sciences and Engineering Conference  5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations  the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014, 2014. Scopus, doi:10.1109/BSEC.2014.6867745.
Terrell TR, Bostick R, Rogers GL, Langston MA, Barth J, Bennett E, Sloane R, Galloway L, Cantu RC, Mihelic FM. Association of APOE and other genetic polymorphisms with prospective concussion risk in a prospective cohort study of college athletes. Proceedings of the 2014 Biomedical Sciences and Engineering Conference  5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations  the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014. 2014.

Published In

Proceedings of the 2014 Biomedical Sciences and Engineering Conference 5th Annual Ornl Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations the Multi Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, Bsec 2014

DOI

ISBN

9781479941599

Publication Date

July 29, 2014