A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance.
Publication
, Journal Article
Howard, BA; James, OG; Perkins, JM; Pagnanelli, RA; Borges-Neto, S; Reiman, RE
Published in: SAGE Open Med Case Rep
2017
In thyroid cancer patients with renal impairment or other complicating factors, it is important to maximize I-131 therapy efficacy while minimizing bone marrow and lung damage. We developed a web-based calculator based on a modified Benua and Leeper method to calculate the maximum I-131 dose to reduce the risk of these toxicities, based on the effective renal clearance of I-123 as measured from two whole-body I-123 scans, performed at 0 and 24 h post-administration.
Duke Scholars
Published In
SAGE Open Med Case Rep
DOI
ISSN
2050-313X
Publication Date
2017
Volume
5
Start / End Page
2050313X17745203
Location
England
Related Subject Headings
- 42 Health sciences
- 32 Biomedical and clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Howard, B. A., James, O. G., Perkins, J. M., Pagnanelli, R. A., Borges-Neto, S., & Reiman, R. E. (2017). A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance. SAGE Open Med Case Rep, 5, 2050313X17745203. https://doi.org/10.1177/2050313X17745203
Howard, Brandon A., Olga G. James, Jennifer M. Perkins, Robert A. Pagnanelli, Salvador Borges-Neto, and Robert E. Reiman. “A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance.” SAGE Open Med Case Rep 5 (2017): 2050313X17745203. https://doi.org/10.1177/2050313X17745203.
Howard BA, James OG, Perkins JM, Pagnanelli RA, Borges-Neto S, Reiman RE. A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance. SAGE Open Med Case Rep. 2017;5:2050313X17745203.
Howard, Brandon A., et al. “A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance.” SAGE Open Med Case Rep, vol. 5, 2017, p. 2050313X17745203. Pubmed, doi:10.1177/2050313X17745203.
Howard BA, James OG, Perkins JM, Pagnanelli RA, Borges-Neto S, Reiman RE. A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance. SAGE Open Med Case Rep. 2017;5:2050313X17745203.
Published In
SAGE Open Med Case Rep
DOI
ISSN
2050-313X
Publication Date
2017
Volume
5
Start / End Page
2050313X17745203
Location
England
Related Subject Headings
- 42 Health sciences
- 32 Biomedical and clinical sciences