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The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug.

Publication ,  Journal Article
George, S; Dauwe, K; McBurney, A; Ward, J
Published in: Br J Clin Pharmacol
April 1983

The effects of food ingestion on the absorption of timegadine, a recently synthesised non-steroidal anti-inflammatory drug, was studied in ten healthy volunteers. It was found that food enhanced the absorption of timegadine as shown by increased peak plasma concentrations (Cmax), decreased time taken to achieve these concentrations (tmax), and increased area under the plasma concentration time curve (AUC).

Duke Scholars

Published In

Br J Clin Pharmacol

DOI

ISSN

0306-5251

Publication Date

April 1983

Volume

15

Issue

4

Start / End Page

495 / 498

Location

England

Related Subject Headings

  • Time Factors
  • Pharmacology & Pharmacy
  • Humans
  • Guanidines
  • Eating
  • Biological Availability
  • Anti-Inflammatory Agents
  • Adult
  • Absorption
  • 1115 Pharmacology and Pharmaceutical Sciences
 

Citation

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Chicago
ICMJE
MLA
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George, S., Dauwe, K., McBurney, A., & Ward, J. (1983). The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug. Br J Clin Pharmacol, 15(4), 495–498. https://doi.org/10.1111/j.1365-2125.1983.tb01537.x
George, S., K. Dauwe, A. McBurney, and J. Ward. “The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug.Br J Clin Pharmacol 15, no. 4 (April 1983): 495–98. https://doi.org/10.1111/j.1365-2125.1983.tb01537.x.
George S, Dauwe K, McBurney A, Ward J. The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug. Br J Clin Pharmacol. 1983 Apr;15(4):495–8.
George, S., et al. “The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug.Br J Clin Pharmacol, vol. 15, no. 4, Apr. 1983, pp. 495–98. Pubmed, doi:10.1111/j.1365-2125.1983.tb01537.x.
George S, Dauwe K, McBurney A, Ward J. The influence of food intake on the bioavailability of timegadine, a novel non-steroidal anti-inflammatory drug. Br J Clin Pharmacol. 1983 Apr;15(4):495–498.
Journal cover image

Published In

Br J Clin Pharmacol

DOI

ISSN

0306-5251

Publication Date

April 1983

Volume

15

Issue

4

Start / End Page

495 / 498

Location

England

Related Subject Headings

  • Time Factors
  • Pharmacology & Pharmacy
  • Humans
  • Guanidines
  • Eating
  • Biological Availability
  • Anti-Inflammatory Agents
  • Adult
  • Absorption
  • 1115 Pharmacology and Pharmaceutical Sciences