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Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors.

Publication ,  Journal Article
Lariviere, B; Garman, KS; Ferguson, NL; Fisher, DA; Jokerst, NM
Published in: Biomed Opt Express
March 1, 2018

Early detection and surveillance of disease progression in epithelial tissue is key to improving long term patient outcomes for colon and esophageal cancers, which account for nearly a quarter of cancer related mortalities worldwide. Spatially resolved diffuse reflectance spectroscopy (SRDRS) is a non-invasive optical technique to sense biological changes at the cellular and sub-cellular level that occur when normal tissue becomes diseased, and has the potential to significantly improve the current standard of care for endoscopic gastrointestinal (GI) screening. Herein the design, fabrication, and characterization of the first custom SRDRS device to enable endoscopic SRDRS GI tissue characterization using a custom silicon (Si) thin film multi-pixel endoscopic optical sensor (MEOS) is described.

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Published In

Biomed Opt Express

DOI

ISSN

2156-7085

Publication Date

March 1, 2018

Volume

9

Issue

3

Start / End Page

1164 / 1176

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics
 

Citation

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ICMJE
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Lariviere, B., Garman, K. S., Ferguson, N. L., Fisher, D. A., & Jokerst, N. M. (2018). Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors. Biomed Opt Express, 9(3), 1164–1176. https://doi.org/10.1364/BOE.9.001164
Lariviere, Ben, Katherine S. Garman, N Lynn Ferguson, Deborah A. Fisher, and Nan M. Jokerst. “Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors.Biomed Opt Express 9, no. 3 (March 1, 2018): 1164–76. https://doi.org/10.1364/BOE.9.001164.
Lariviere B, Garman KS, Ferguson NL, Fisher DA, Jokerst NM. Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors. Biomed Opt Express. 2018 Mar 1;9(3):1164–76.
Lariviere, Ben, et al. “Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors.Biomed Opt Express, vol. 9, no. 3, Mar. 2018, pp. 1164–76. Pubmed, doi:10.1364/BOE.9.001164.
Lariviere B, Garman KS, Ferguson NL, Fisher DA, Jokerst NM. Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors. Biomed Opt Express. 2018 Mar 1;9(3):1164–1176.
Journal cover image

Published In

Biomed Opt Express

DOI

ISSN

2156-7085

Publication Date

March 1, 2018

Volume

9

Issue

3

Start / End Page

1164 / 1176

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics