Encyclopedia of Biological Chemistry: Second Edition
Centromeres
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Sullivan, BA
February 15, 2013
The centromere is essential for accurate segregation of genetic material in both meiosis and mitosis. It is the site of the primary constriction on metaphase chromosomes. Functionally, it is where proteins of the kinetochore assemble to hold sister chromatids together and to guide chromosome movement during cell division. Centromeric sequence is distinct and diverse in different organisms, yet, chromatin organization of centromeres is similar, emphasizing shared epigenetic, rather than sequence-dependent, aspects of this critical locus.
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Publication Date
February 15, 2013
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446 / 450
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Sullivan, B. A. (2013). Centromeres. In Encyclopedia of Biological Chemistry: Second Edition (pp. 446–450). https://doi.org/10.1016/B978-0-12-378630-2.00471-0
Sullivan, B. A. “Centromeres.” In Encyclopedia of Biological Chemistry: Second Edition, 446–50, 2013. https://doi.org/10.1016/B978-0-12-378630-2.00471-0.
Sullivan BA. Centromeres. In: Encyclopedia of Biological Chemistry: Second Edition. 2013. p. 446–50.
Sullivan, B. A. “Centromeres.” Encyclopedia of Biological Chemistry: Second Edition, 2013, pp. 446–50. Scopus, doi:10.1016/B978-0-12-378630-2.00471-0.
Sullivan BA. Centromeres. Encyclopedia of Biological Chemistry: Second Edition. 2013. p. 446–450.
DOI
Publication Date
February 15, 2013
Start / End Page
446 / 450