Cooling the Itch via TRPM8.
Publication
, Journal Article
Liu, B; Jordt, S-E
Published in: J Invest Dermatol
June 2018
Cooling is an effective temporary remedy for itch, bringing welcome relief to itchy insect bites, nettle stings, poison ivy, atopic dermatitis, and psoriasis. Menthol, causing a cooling sensation, has similar itch-relieving effects. Palkar et al. demonstrate that TRPM8, a menthol- and cold-activated ion channel, is essential for cooling to relieve itch, suggesting that pharmacologic TRPM8 activation should be explored further as an antipruritic strategy.
Duke Scholars
Published In
J Invest Dermatol
DOI
EISSN
1523-1747
Publication Date
June 2018
Volume
138
Issue
6
Start / End Page
1254 / 1256
Location
United States
Related Subject Headings
- TRPM Cation Channels
- Neurons
- Menthol
- Dermatology & Venereal Diseases
- 3202 Clinical sciences
- 1112 Oncology and Carcinogenesis
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Liu, B., & Jordt, S.-E. (2018). Cooling the Itch via TRPM8. J Invest Dermatol, 138(6), 1254–1256. https://doi.org/10.1016/j.jid.2018.01.020
Liu, Boyi, and Sven-Eric Jordt. “Cooling the Itch via TRPM8.” J Invest Dermatol 138, no. 6 (June 2018): 1254–56. https://doi.org/10.1016/j.jid.2018.01.020.
Liu B, Jordt S-E. Cooling the Itch via TRPM8. J Invest Dermatol. 2018 Jun;138(6):1254–6.
Liu, Boyi, and Sven-Eric Jordt. “Cooling the Itch via TRPM8.” J Invest Dermatol, vol. 138, no. 6, June 2018, pp. 1254–56. Pubmed, doi:10.1016/j.jid.2018.01.020.
Liu B, Jordt S-E. Cooling the Itch via TRPM8. J Invest Dermatol. 2018 Jun;138(6):1254–1256.
Published In
J Invest Dermatol
DOI
EISSN
1523-1747
Publication Date
June 2018
Volume
138
Issue
6
Start / End Page
1254 / 1256
Location
United States
Related Subject Headings
- TRPM Cation Channels
- Neurons
- Menthol
- Dermatology & Venereal Diseases
- 3202 Clinical sciences
- 1112 Oncology and Carcinogenesis
- 1103 Clinical Sciences