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Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices.

Publication ,  Journal Article
Feder, R; Posner, S; Qin, Y; Zheng, J; Chow, S-C; Garman, KS
Published in: Helicobacter
December 2018

BACKGROUND & AIMS: Guidelines recommend that patients with Helicobacter pylori (H. pylori)-associated peptic ulcer disease (PUD) receive H. pylori eradication therapy followed by post-treatment testing to prove eradication; however, post-treatment testing rates are suboptimal and barriers to testing are poorly understood. Our aim was to identify factors that predicted receipt of post-treatment testing. METHODS: We performed a retrospective cohort study of 152 patients with H. pylori-associated PUD diagnosed between 2007 and 2015 at a large tertiary medical center in the United States, who received standard eradication therapy and ambulatory follow-up within one year. The primary outcome of interest was receipt of post-treatment testing. Logistic regression models compared post-treatment testing rates in those diagnosed while outpatient vs inpatient, patients with vs without repeat endoscopy, and patients with vs without gastroenterology (GI) clinic follow-up. Propensity scores controlled for age, sex, race, ulcer location, and symptom persistence. RESULTS: Among 152 patients, 67 (44%) patients received post-treatment testing. There were significant differences in post-treatment testing rates in those diagnosed as outpatients vs inpatients (57% vs 33%; OR 3.87, P = 0.001) and in patients with vs without GI follow-up (62% vs 11%; OR 9.85, P < 0.0001). CONCLUSIONS: The rate of testing for eradication after treatment in patients with H. pylori- associated PUD was low. However, this was significantly improved in patients who have GI follow-up and whose diagnosis was made in the outpatient setting. Our study demonstrates a clear opportunity for quality improvement initiatives.

Duke Scholars

Published In

Helicobacter

DOI

EISSN

1523-5378

Publication Date

December 2018

Volume

23

Issue

6

Start / End Page

e12540

Location

England

Related Subject Headings

  • Young Adult
  • Retrospective Studies
  • Peptic Ulcer
  • Middle Aged
  • Male
  • Logistic Models
  • Humans
  • Helicobacter pylori
  • Helicobacter Infections
  • Gastroenterology & Hepatology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Feder, R., Posner, S., Qin, Y., Zheng, J., Chow, S.-C., & Garman, K. S. (2018). Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices. Helicobacter, 23(6), e12540. https://doi.org/10.1111/hel.12540
Feder, Rachel, Shai Posner, Yi Qin, Jiayin Zheng, Shein-Chung Chow, and Katherine S. Garman. “Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices.Helicobacter 23, no. 6 (December 2018): e12540. https://doi.org/10.1111/hel.12540.
Feder R, Posner S, Qin Y, Zheng J, Chow S-C, Garman KS. Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices. Helicobacter. 2018 Dec;23(6):e12540.
Feder, Rachel, et al. “Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices.Helicobacter, vol. 23, no. 6, Dec. 2018, p. e12540. Pubmed, doi:10.1111/hel.12540.
Feder R, Posner S, Qin Y, Zheng J, Chow S-C, Garman KS. Helicobacter pylori-associated peptic ulcer disease: A retrospective analysis of post-treatment testing practices. Helicobacter. 2018 Dec;23(6):e12540.
Journal cover image

Published In

Helicobacter

DOI

EISSN

1523-5378

Publication Date

December 2018

Volume

23

Issue

6

Start / End Page

e12540

Location

England

Related Subject Headings

  • Young Adult
  • Retrospective Studies
  • Peptic Ulcer
  • Middle Aged
  • Male
  • Logistic Models
  • Humans
  • Helicobacter pylori
  • Helicobacter Infections
  • Gastroenterology & Hepatology