Are Neuropeptide-Reactive T Cells behind Narcolepsy?
Publication
, Journal Article
Deerhake, ME; Barclay, WE; Shinohara, ML
Published in: Immunity
November 20, 2018
Researchers have previously hypothesized autoimmune origins for narcolepsy on the basis of its strong genetic association with an MHC class II allele. In a recent issue of Nature, Latorre et al. (2018) discovered that narcolepsy patients had autoreactive T cells specific to the neuronal antigen hypocretin, providing more evidence of the potential immune origin of the disease.
Duke Scholars
Published In
Immunity
DOI
EISSN
1097-4180
Publication Date
November 20, 2018
Volume
49
Issue
5
Start / End Page
796 / 798
Location
United States
Related Subject Headings
- T-Lymphocytes
- Orexins
- Neuropeptides
- Neurons
- Narcolepsy
- Immunology
- Humans
- Autoantigens
- 3204 Immunology
- 1107 Immunology
Citation
APA
Chicago
ICMJE
MLA
NLM
Deerhake, M. E., Barclay, W. E., & Shinohara, M. L. (2018). Are Neuropeptide-Reactive T Cells behind Narcolepsy? Immunity, 49(5), 796–798. https://doi.org/10.1016/j.immuni.2018.11.002
Deerhake, M Elizabeth, William E. Barclay, and Mari L. Shinohara. “Are Neuropeptide-Reactive T Cells behind Narcolepsy?” Immunity 49, no. 5 (November 20, 2018): 796–98. https://doi.org/10.1016/j.immuni.2018.11.002.
Deerhake ME, Barclay WE, Shinohara ML. Are Neuropeptide-Reactive T Cells behind Narcolepsy? Immunity. 2018 Nov 20;49(5):796–8.
Deerhake, M. Elizabeth, et al. “Are Neuropeptide-Reactive T Cells behind Narcolepsy?” Immunity, vol. 49, no. 5, Nov. 2018, pp. 796–98. Pubmed, doi:10.1016/j.immuni.2018.11.002.
Deerhake ME, Barclay WE, Shinohara ML. Are Neuropeptide-Reactive T Cells behind Narcolepsy? Immunity. 2018 Nov 20;49(5):796–798.
Published In
Immunity
DOI
EISSN
1097-4180
Publication Date
November 20, 2018
Volume
49
Issue
5
Start / End Page
796 / 798
Location
United States
Related Subject Headings
- T-Lymphocytes
- Orexins
- Neuropeptides
- Neurons
- Narcolepsy
- Immunology
- Humans
- Autoantigens
- 3204 Immunology
- 1107 Immunology