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Making a Tissue Microarray.

Publication ,  Journal Article
Koo, M; Squires, JM; Ying, D; Huang, J
Published in: Methods Mol Biol
2019

Tissue microarray (TMA) is a widely used, high-throughput, cost-effective, and tissue and reagent-conserving method of performing molecular analysis. Multiple donor tissue cores are procured and transferred into a recipient TMA block for simultaneous differential and comparative molecular profiling under theoretically identical performance conditions. Described herein is a discussion of the theory behind the TMA, an overview of the concepts and principles of TMA design and construction, a brief summary of its advantages and disadvantages, and a sample protocol of TMA construction.

Duke Scholars

Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2019

Volume

1897

Start / End Page

313 / 323

Location

United States

Related Subject Headings

  • Tissue Array Analysis
  • Paraffin Embedding
  • Humans
  • Developmental Biology
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Koo, M., Squires, J. M., Ying, D., & Huang, J. (2019). Making a Tissue Microarray. Methods Mol Biol, 1897, 313–323. https://doi.org/10.1007/978-1-4939-8935-5_27
Koo, Matthew, Jill M. Squires, Daphne Ying, and Jiaoti Huang. “Making a Tissue Microarray.Methods Mol Biol 1897 (2019): 313–23. https://doi.org/10.1007/978-1-4939-8935-5_27.
Koo M, Squires JM, Ying D, Huang J. Making a Tissue Microarray. Methods Mol Biol. 2019;1897:313–23.
Koo, Matthew, et al. “Making a Tissue Microarray.Methods Mol Biol, vol. 1897, 2019, pp. 313–23. Pubmed, doi:10.1007/978-1-4939-8935-5_27.
Koo M, Squires JM, Ying D, Huang J. Making a Tissue Microarray. Methods Mol Biol. 2019;1897:313–323.

Published In

Methods Mol Biol

DOI

EISSN

1940-6029

Publication Date

2019

Volume

1897

Start / End Page

313 / 323

Location

United States

Related Subject Headings

  • Tissue Array Analysis
  • Paraffin Embedding
  • Humans
  • Developmental Biology
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0601 Biochemistry and Cell Biology
  • 0399 Other Chemical Sciences