TET2 Deficiency Sets the Stage for B-cell Lymphoma.
Publication
, Journal Article
Shingleton, JR; Dave, SS
Published in: Cancer Discov
December 2018
TET2 is a well-established tumor suppressor in the context of myeloid malignancies, but its role in lymphoma development has been less clear. In this issue of Cancer Discovery, Dominguez and colleagues report that TET2 function is critical for germinal center exit and plasma cell differentiation, and its deficiency can lead to B-cell lymphoma phenotypes.See related article by Dominguez et al., p. 1632.
Duke Scholars
Published In
Cancer Discov
DOI
EISSN
2159-8290
Publication Date
December 2018
Volume
8
Issue
12
Start / End Page
1515 / 1517
Location
United States
Related Subject Headings
- Proto-Oncogene Proteins
- Lymphoma, B-Cell
- Hyperplasia
- Humans
- Germinal Center
- Dioxygenases
- DNA-Binding Proteins
- B-Lymphocytes
- 3211 Oncology and carcinogenesis
- 3101 Biochemistry and cell biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Shingleton, J. R., & Dave, S. S. (2018). TET2 Deficiency Sets the Stage for B-cell Lymphoma. Cancer Discov, 8(12), 1515–1517. https://doi.org/10.1158/2159-8290.CD-18-1143
Shingleton, Jennifer R., and Sandeep S. Dave. “TET2 Deficiency Sets the Stage for B-cell Lymphoma.” Cancer Discov 8, no. 12 (December 2018): 1515–17. https://doi.org/10.1158/2159-8290.CD-18-1143.
Shingleton JR, Dave SS. TET2 Deficiency Sets the Stage for B-cell Lymphoma. Cancer Discov. 2018 Dec;8(12):1515–7.
Shingleton, Jennifer R., and Sandeep S. Dave. “TET2 Deficiency Sets the Stage for B-cell Lymphoma.” Cancer Discov, vol. 8, no. 12, Dec. 2018, pp. 1515–17. Pubmed, doi:10.1158/2159-8290.CD-18-1143.
Shingleton JR, Dave SS. TET2 Deficiency Sets the Stage for B-cell Lymphoma. Cancer Discov. 2018 Dec;8(12):1515–1517.
Published In
Cancer Discov
DOI
EISSN
2159-8290
Publication Date
December 2018
Volume
8
Issue
12
Start / End Page
1515 / 1517
Location
United States
Related Subject Headings
- Proto-Oncogene Proteins
- Lymphoma, B-Cell
- Hyperplasia
- Humans
- Germinal Center
- Dioxygenases
- DNA-Binding Proteins
- B-Lymphocytes
- 3211 Oncology and carcinogenesis
- 3101 Biochemistry and cell biology