State-of-the-art microwire array design for chronic neural recordings in behaving animals

Over the last two decades, many laboratories around the world have started to rely on microelectrode arrays formed by ne microwires, organized in different geometrical congurations, to chronically record the extracellular activity of populations of individual neurons in both anesthetized and behaving animals (Nicolelis et al. 1997, 2003; Lebedev et al. 2006; Verloop and Holsheimer 1984; Williams et al. 1999). As the eld of chronic multielectrode recordings evolved, so did the designs of such microwire-based arrays.

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Author Miguel Angelo L. Nicolelis Neurobiology