Clearance from the anterior chamber of RBCs from human diabetics.
Publication
, Journal Article
Williams, GA; Hatchell, DL; Collier, BD; Knobel, J
Published in: Arch Ophthalmol
June 1984
Erythrocytes from diabetic patients manifest decreased deformability and increased adherence. These abnormal membrane properties may diminish the ability of erythrocytes (RBCs) from diabetics to undergo deformation in passage through the trabecular meshwork. Using sodium chromate Cr 51-labeled RBCs from type I diabetic patients with proliferative retinopathy and normal control subjects, we studied RBC clearance from the rabbit anterior chamber. The mean time for 50% clearance (T50) of RBCs from diabetics (76 hours) was significantly longer than that for RBCs from normal subjects (19.5 hours). In this model, RBCs from diabetics have a slower clearance from the anterior chamber than do RBCs from normal subjects.
Duke Scholars
Published In
Arch Ophthalmol
DOI
ISSN
0003-9950
Publication Date
June 1984
Volume
102
Issue
6
Start / End Page
930 / 931
Location
United States
Related Subject Headings
- Rabbits
- Ophthalmology & Optometry
- Metabolic Clearance Rate
- Hyphema
- Humans
- Erythrocytes
- Diabetic Retinopathy
- Diabetes Mellitus, Type 1
- Chromium Radioisotopes
- Anterior Chamber
Citation
APA
Chicago
ICMJE
MLA
NLM
Williams, G. A., Hatchell, D. L., Collier, B. D., & Knobel, J. (1984). Clearance from the anterior chamber of RBCs from human diabetics. Arch Ophthalmol, 102(6), 930–931. https://doi.org/10.1001/archopht.1984.01040030750038
Williams, G. A., D. L. Hatchell, B. D. Collier, and J. Knobel. “Clearance from the anterior chamber of RBCs from human diabetics.” Arch Ophthalmol 102, no. 6 (June 1984): 930–31. https://doi.org/10.1001/archopht.1984.01040030750038.
Williams GA, Hatchell DL, Collier BD, Knobel J. Clearance from the anterior chamber of RBCs from human diabetics. Arch Ophthalmol. 1984 Jun;102(6):930–1.
Williams, G. A., et al. “Clearance from the anterior chamber of RBCs from human diabetics.” Arch Ophthalmol, vol. 102, no. 6, June 1984, pp. 930–31. Pubmed, doi:10.1001/archopht.1984.01040030750038.
Williams GA, Hatchell DL, Collier BD, Knobel J. Clearance from the anterior chamber of RBCs from human diabetics. Arch Ophthalmol. 1984 Jun;102(6):930–931.
Published In
Arch Ophthalmol
DOI
ISSN
0003-9950
Publication Date
June 1984
Volume
102
Issue
6
Start / End Page
930 / 931
Location
United States
Related Subject Headings
- Rabbits
- Ophthalmology & Optometry
- Metabolic Clearance Rate
- Hyphema
- Humans
- Erythrocytes
- Diabetic Retinopathy
- Diabetes Mellitus, Type 1
- Chromium Radioisotopes
- Anterior Chamber