Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management.
Publication
, Journal Article
Previs, RA; Secord, AA
Published in: Obstet Gynecol Clin North Am
March 2019
Ovarian cancer treatment continues to evolve. Despite aggressive surgery and chemotherapy, most women will ultimately die from disease. Improvement in disease control are due to the incorporation of molecular targeted agents and the adoption of maintenance therapy. Maintenance therapy has been shown to enhance progression-free survival. Recent surgical trials have evaluated the role of neoadjuvant chemotherapy versus primary debulking at the time of diagnosis in advanced stage ovarian cancer. The role of lymph node dissection and secondary cytoreductive surgeries have also been evaluated. This article reviews contemporary trials of maintenance therapy and novel drug development.
Duke Scholars
Published In
Obstet Gynecol Clin North Am
DOI
EISSN
1558-0474
Publication Date
March 2019
Volume
46
Issue
1
Start / End Page
67 / 88
Location
United States
Related Subject Headings
- Standard of Care
- Patient Selection
- Ovarian Neoplasms
- Obstetrics & Reproductive Medicine
- Neoadjuvant Therapy
- Humans
- Female
- Cytoreduction Surgical Procedures
- Clinical Trials as Topic
- 4204 Midwifery
Citation
APA
Chicago
ICMJE
MLA
NLM
Previs, R. A., & Secord, A. A. (2019). Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management. Obstet Gynecol Clin North Am, 46(1), 67–88. https://doi.org/10.1016/j.ogc.2018.09.005
Previs, Rebecca Ann, and Angeles Alvarez Secord. “Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management.” Obstet Gynecol Clin North Am 46, no. 1 (March 2019): 67–88. https://doi.org/10.1016/j.ogc.2018.09.005.
Previs RA, Secord AA. Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management. Obstet Gynecol Clin North Am. 2019 Mar;46(1):67–88.
Previs, Rebecca Ann, and Angeles Alvarez Secord. “Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management.” Obstet Gynecol Clin North Am, vol. 46, no. 1, Mar. 2019, pp. 67–88. Pubmed, doi:10.1016/j.ogc.2018.09.005.
Previs RA, Secord AA. Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management. Obstet Gynecol Clin North Am. 2019 Mar;46(1):67–88.
Published In
Obstet Gynecol Clin North Am
DOI
EISSN
1558-0474
Publication Date
March 2019
Volume
46
Issue
1
Start / End Page
67 / 88
Location
United States
Related Subject Headings
- Standard of Care
- Patient Selection
- Ovarian Neoplasms
- Obstetrics & Reproductive Medicine
- Neoadjuvant Therapy
- Humans
- Female
- Cytoreduction Surgical Procedures
- Clinical Trials as Topic
- 4204 Midwifery