
A systems-based model of Alzheimer's disease.
Publication
, Journal Article
Tang, Y; Lutz, MW; Xing, Y
Published in: Alzheimers Dement
January 2019
The new National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease has been developed to accelerate drug discovery and offer a common structure and language to construct new Alzheimer's disease conceptual models. However, as a "complex" disease, a model based on systems-level understanding is needed to accommodate the complex, interacting etiologic pathways and the system-level changes associated with Alzheimer's disease pathogenesis and interventions that are currently known and which will be identified in the future. To accomplish this, the evolution of the structure of the research framework itself should be encouraged.
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Published In
Alzheimers Dement
DOI
EISSN
1552-5279
Publication Date
January 2019
Volume
15
Issue
1
Start / End Page
168 / 171
Location
United States
Related Subject Headings
- United States
- Systems Biology
- National Institute on Aging (U.S.)
- Humans
- Geriatrics
- Alzheimer Disease
- 5202 Biological psychology
- 3209 Neurosciences
- 3202 Clinical sciences
- 1109 Neurosciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Tang, Y., Lutz, M. W., & Xing, Y. (2019). A systems-based model of Alzheimer's disease. Alzheimers Dement, 15(1), 168–171. https://doi.org/10.1016/j.jalz.2018.06.3058
Tang, Yi, Michael W. Lutz, and Yi Xing. “A systems-based model of Alzheimer's disease.” Alzheimers Dement 15, no. 1 (January 2019): 168–71. https://doi.org/10.1016/j.jalz.2018.06.3058.
Tang Y, Lutz MW, Xing Y. A systems-based model of Alzheimer's disease. Alzheimers Dement. 2019 Jan;15(1):168–71.
Tang, Yi, et al. “A systems-based model of Alzheimer's disease.” Alzheimers Dement, vol. 15, no. 1, Jan. 2019, pp. 168–71. Pubmed, doi:10.1016/j.jalz.2018.06.3058.
Tang Y, Lutz MW, Xing Y. A systems-based model of Alzheimer's disease. Alzheimers Dement. 2019 Jan;15(1):168–171.

Published In
Alzheimers Dement
DOI
EISSN
1552-5279
Publication Date
January 2019
Volume
15
Issue
1
Start / End Page
168 / 171
Location
United States
Related Subject Headings
- United States
- Systems Biology
- National Institute on Aging (U.S.)
- Humans
- Geriatrics
- Alzheimer Disease
- 5202 Biological psychology
- 3209 Neurosciences
- 3202 Clinical sciences
- 1109 Neurosciences