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Residential environment and breast cancer incidence and mortality: a systematic review and meta-analysis.

Publication ,  Journal Article
Akinyemiju, TF; Genkinger, JM; Farhat, M; Wilson, A; Gary-Webb, TL; Tehranifar, P
Published in: BMC Cancer
March 28, 2015

BACKGROUND: Factors beyond the individual level such as those characterizing the residential environment may be important to breast cancer outcomes. We provide a systematic review and results of meta-analysis of the published empirical literature on the associations between breast cancer risk and mortality and features of the residential environment. METHODS: Using PRISMA guidelines, we searched four electronic databases and manually searched the references of selected articles for studies that were published before June 2013. We selected English language articles that presented data on adult breast cancer incidence or mortality in relation to at least one area-based residential (ABR) independent variable. RESULTS: We reviewed 31 eligible studies, and observed variations in ABR construct definition and measurement, study design, and analytic approach. The most common ABR measures were indicators of socioeconomic status (SES) (e.g., income, education, summary measures of several SES indicators or composite SES). We observed positive associations between breast cancer incidence and urbanization (Pooled RR for urban vs. rural: 1.09. 95% CI: 1.01, 1.19), ABR income (Pooled RR for highest vs. lowest ABR income: 1.17, 95% CI: 1.15, 1.19) and ABR composite SES (Pooled RR for highest vs. lowest ABR composite SES: 1.25, 95% CI: 1.08, 1.44). We did not observe consistent associations between any ABR measures and breast cancer mortality. CONCLUSIONS: The findings suggest modest positive associations between urbanization and residential area socioeconomic environment and breast cancer incidence. Further studies should address conceptual and methodological gaps in the current publications to enable inference regarding the influence of the residential environment on breast cancer.

Duke Scholars

Published In

BMC Cancer

DOI

EISSN

1471-2407

Publication Date

March 28, 2015

Volume

15

Start / End Page

191

Location

England

Related Subject Headings

  • Social Environment
  • Social Class
  • Oncology & Carcinogenesis
  • Middle Aged
  • Income
  • Humans
  • Female
  • Breast Neoplasms
  • Aged
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
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Akinyemiju, T. F., Genkinger, J. M., Farhat, M., Wilson, A., Gary-Webb, T. L., & Tehranifar, P. (2015). Residential environment and breast cancer incidence and mortality: a systematic review and meta-analysis. BMC Cancer, 15, 191. https://doi.org/10.1186/s12885-015-1098-z
Akinyemiju, Tomi F., Jeanine M. Genkinger, Maggie Farhat, Adrienne Wilson, Tiffany L. Gary-Webb, and Parisa Tehranifar. “Residential environment and breast cancer incidence and mortality: a systematic review and meta-analysis.BMC Cancer 15 (March 28, 2015): 191. https://doi.org/10.1186/s12885-015-1098-z.
Akinyemiju TF, Genkinger JM, Farhat M, Wilson A, Gary-Webb TL, Tehranifar P. Residential environment and breast cancer incidence and mortality: a systematic review and meta-analysis. BMC Cancer. 2015 Mar 28;15:191.
Akinyemiju, Tomi F., et al. “Residential environment and breast cancer incidence and mortality: a systematic review and meta-analysis.BMC Cancer, vol. 15, Mar. 2015, p. 191. Pubmed, doi:10.1186/s12885-015-1098-z.
Akinyemiju TF, Genkinger JM, Farhat M, Wilson A, Gary-Webb TL, Tehranifar P. Residential environment and breast cancer incidence and mortality: a systematic review and meta-analysis. BMC Cancer. 2015 Mar 28;15:191.
Journal cover image

Published In

BMC Cancer

DOI

EISSN

1471-2407

Publication Date

March 28, 2015

Volume

15

Start / End Page

191

Location

England

Related Subject Headings

  • Social Environment
  • Social Class
  • Oncology & Carcinogenesis
  • Middle Aged
  • Income
  • Humans
  • Female
  • Breast Neoplasms
  • Aged
  • Adult