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Management of recurrent Ewing sarcoma: challenges and approaches.

Publication ,  Journal Article
Van Mater, D; Wagner, L
Published in: Onco Targets Ther
2019

Although many patients with newly diagnosed Ewing sarcoma can become long-term survivors, relapse remains an important clinical problem for which there is no standard approach. Several prognostic factors have been identified, and these may help guide patient counseling and therapy decisions. A variety of chemotherapy regimens have produced responses in patients with recurrent Ewing sarcoma, but no comparative studies have been completed to show superiority of any one particular approach. In addition, the optimum length of therapy for salvage regimens and use of local control measures remains unknown. The likelihood of cure remains low and the gaps in our knowledge are great, and so enrollment on clinical trials should be strongly encouraged for these patients when feasible. Because Ewing sarcoma is relatively rare, some pediatric and adult oncologists may be less familiar with the management of relapsed patients. In this review, we address common questions facing the clinician and patient, and provide an update on new strategies for therapy.

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Published In

Onco Targets Ther

DOI

ISSN

1178-6930

Publication Date

2019

Volume

12

Start / End Page

2279 / 2288

Location

New Zealand

Related Subject Headings

  • 1112 Oncology and Carcinogenesis
 

Citation

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Chicago
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MLA
NLM
Van Mater, D., & Wagner, L. (2019). Management of recurrent Ewing sarcoma: challenges and approaches. Onco Targets Ther, 12, 2279–2288. https://doi.org/10.2147/OTT.S170585
Van Mater, David, and Lars Wagner. “Management of recurrent Ewing sarcoma: challenges and approaches.Onco Targets Ther 12 (2019): 2279–88. https://doi.org/10.2147/OTT.S170585.
Van Mater D, Wagner L. Management of recurrent Ewing sarcoma: challenges and approaches. Onco Targets Ther. 2019;12:2279–88.
Van Mater, David, and Lars Wagner. “Management of recurrent Ewing sarcoma: challenges and approaches.Onco Targets Ther, vol. 12, 2019, pp. 2279–88. Pubmed, doi:10.2147/OTT.S170585.
Van Mater D, Wagner L. Management of recurrent Ewing sarcoma: challenges and approaches. Onco Targets Ther. 2019;12:2279–2288.

Published In

Onco Targets Ther

DOI

ISSN

1178-6930

Publication Date

2019

Volume

12

Start / End Page

2279 / 2288

Location

New Zealand

Related Subject Headings

  • 1112 Oncology and Carcinogenesis