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A computational fluid dynamics analysis of the effects of size and shape of anterior nasal septal perforations.

Publication ,  Journal Article
Farzal, Z; Del Signore, AG; Zanation, AM; Ebert, CS; Frank-Ito, D; Kimbell, JS; Senior, BA
Published in: Rhinology
April 1, 2019

BACKGROUND: Nasal septal perforations (NSPs) often cause bleeding, crusting, obstruction, and/or whistling. The objective was to analyze the impact of anterior NSP size and shape on nasal physiology using computational fluid dynamics (CFD). METHODS: A 3-dimensional model of the nasal cavity was constructed from a radiologically normal CT scan using imaging software. Anterior NSPs (ovoid (ONSP): 0.5, 1, 2, and 3 cm long anterior-to-posteriorly and round (RNSP, 0.5 and 1 cm)) were virtually created in the model and divided into ventral, dorsal, anterior, and posterior regions. Steady-state inspiratory airflow, heat, and water vapor transport were simulated using Fluent CFD software. Air crossover through the perforation, wall shear, heat flux, water vapor flux, resistance, and humidification were analyzed. RESULTS: Air crossover and wall shear increased with perforation size. Regionally, wall shear and heat and water vapor flux were highest posteriorly and lowest anteriorly, generally increasing with size in those regions. RNSPs had greater heat and water vapor flux compared to corresponding size ONSPs. Resistance decreased by 10% or more from normal only in the 3 cm ONSP. Maximum water content was achieved more posteriorly in larger NSP nasal cavities. CONCLUSIONS: High wall shear and heat and water vapor flux in posterior perforation regions may explain the crusting most commonly noted on posterior NSP edges. This preliminary study suggests that larger NSPs have a greater effect on nasal resistance and water content. Decrease in resistance with larger NSP size may be implicated in reported symptomatic improvement following enlargement of NSPs for treatment.

Duke Scholars

Published In

Rhinology

DOI

ISSN

0300-0729

Publication Date

April 1, 2019

Volume

57

Issue

2

Start / End Page

153 / 159

Location

Netherlands

Related Subject Headings

  • Otorhinolaryngology
  • Nose
  • Nasal Septal Perforation
  • Nasal Cavity
  • Hydrodynamics
  • Humans
  • Computer Simulation
  • 3203 Dentistry
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Farzal, Z., Del Signore, A. G., Zanation, A. M., Ebert, C. S., Frank-Ito, D., Kimbell, J. S., & Senior, B. A. (2019). A computational fluid dynamics analysis of the effects of size and shape of anterior nasal septal perforations. Rhinology, 57(2), 153–159. https://doi.org/10.4193/Rhin18.111
Farzal, Z., A. G. Del Signore, A. M. Zanation, C. S. Ebert, D. Frank-Ito, J. S. Kimbell, and B. A. Senior. “A computational fluid dynamics analysis of the effects of size and shape of anterior nasal septal perforations.Rhinology 57, no. 2 (April 1, 2019): 153–59. https://doi.org/10.4193/Rhin18.111.
Farzal Z, Del Signore AG, Zanation AM, Ebert CS, Frank-Ito D, Kimbell JS, et al. A computational fluid dynamics analysis of the effects of size and shape of anterior nasal septal perforations. Rhinology. 2019 Apr 1;57(2):153–9.
Farzal, Z., et al. “A computational fluid dynamics analysis of the effects of size and shape of anterior nasal septal perforations.Rhinology, vol. 57, no. 2, Apr. 2019, pp. 153–59. Pubmed, doi:10.4193/Rhin18.111.
Farzal Z, Del Signore AG, Zanation AM, Ebert CS, Frank-Ito D, Kimbell JS, Senior BA. A computational fluid dynamics analysis of the effects of size and shape of anterior nasal septal perforations. Rhinology. 2019 Apr 1;57(2):153–159.

Published In

Rhinology

DOI

ISSN

0300-0729

Publication Date

April 1, 2019

Volume

57

Issue

2

Start / End Page

153 / 159

Location

Netherlands

Related Subject Headings

  • Otorhinolaryngology
  • Nose
  • Nasal Septal Perforation
  • Nasal Cavity
  • Hydrodynamics
  • Humans
  • Computer Simulation
  • 3203 Dentistry
  • 3202 Clinical sciences
  • 1103 Clinical Sciences