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Monitoring, prevention and treatment of side effects of long-acting neuraxial opioids for post-cesarean analgesia.

Publication ,  Journal Article
Yurashevich, M; Habib, AS
Published in: Int J Obstet Anesth
August 2019

Long-acting neuraxial opioids such as morphine and diamorphine, administered via spinal or epidural routes, are staple components of a multimodal approach to postoperative analgesia following cesarean delivery. The widespread use of neuraxial opioids is due largely to their significant analgesic efficacy and favorable safety profile. The most common side effects of neuraxial opioids are pruritus, nausea and vomiting. These symptoms appear to be dose-related. The most serious complication of neuraxial opioids is respiratory depression, which occurs in 0-0.9% of cases. Hypothermia has also been reported in association with neuraxial morphine use at cesarean delivery. This article will review recent advances in prophylaxis, treatment and monitoring of the side effects of long-acting neuraxial opioids.

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Published In

Int J Obstet Anesth

DOI

EISSN

1532-3374

Publication Date

August 2019

Volume

39

Start / End Page

117 / 128

Location

Netherlands

Related Subject Headings

  • Serotonin Antagonists
  • Respiratory Insufficiency
  • Pruritus
  • Pregnancy
  • Postoperative Nausea and Vomiting
  • Pain, Postoperative
  • Naloxone
  • Morphine
  • Hypothermia
  • Humans
 

Citation

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Yurashevich, M., & Habib, A. S. (2019). Monitoring, prevention and treatment of side effects of long-acting neuraxial opioids for post-cesarean analgesia. Int J Obstet Anesth, 39, 117–128. https://doi.org/10.1016/j.ijoa.2019.03.010
Yurashevich, M., and A. S. Habib. “Monitoring, prevention and treatment of side effects of long-acting neuraxial opioids for post-cesarean analgesia.Int J Obstet Anesth 39 (August 2019): 117–28. https://doi.org/10.1016/j.ijoa.2019.03.010.
Yurashevich, M., and A. S. Habib. “Monitoring, prevention and treatment of side effects of long-acting neuraxial opioids for post-cesarean analgesia.Int J Obstet Anesth, vol. 39, Aug. 2019, pp. 117–28. Pubmed, doi:10.1016/j.ijoa.2019.03.010.
Journal cover image

Published In

Int J Obstet Anesth

DOI

EISSN

1532-3374

Publication Date

August 2019

Volume

39

Start / End Page

117 / 128

Location

Netherlands

Related Subject Headings

  • Serotonin Antagonists
  • Respiratory Insufficiency
  • Pruritus
  • Pregnancy
  • Postoperative Nausea and Vomiting
  • Pain, Postoperative
  • Naloxone
  • Morphine
  • Hypothermia
  • Humans