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Antiglaucoma EP2 Agonists: A Long Road That Led Somewhere.

Publication ,  Journal Article
Woodward, DF; Wang, JW; Stamer, WD; Lütjen-Drecoll, E; Krauss, AH-P; Toris, CB
Published in: J Ocul Pharmacol Ther
November 2019

For >2 decades, EP2 agonists have been the subject of antiglaucoma research and development by scientists in industry and academia around the world. The road has led to the recent approval of the first drug of this class. This article reviews the development of EP2 agonists from conception to clinical approval, discussing pharmacology, structure, biodistribution, therapeutics, and drug delivery. An extensive list of source references is provided for the reader's benefit.

Duke Scholars

Published In

J Ocul Pharmacol Ther

DOI

EISSN

1557-7732

Publication Date

November 2019

Volume

35

Issue

9

Start / End Page

469 / 474

Location

United States

Related Subject Headings

  • Receptors, Prostaglandin E, EP2 Subtype
  • Ophthalmology & Optometry
  • Humans
  • Glaucoma
  • Drug Delivery Systems
  • Antihypertensive Agents
  • Animals
  • 3214 Pharmacology and pharmaceutical sciences
  • 3212 Ophthalmology and optometry
  • 1115 Pharmacology and Pharmaceutical Sciences
 

Citation

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MLA
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Woodward, D. F., Wang, J. W., Stamer, W. D., Lütjen-Drecoll, E., Krauss, A.-P., & Toris, C. B. (2019). Antiglaucoma EP2 Agonists: A Long Road That Led Somewhere. J Ocul Pharmacol Ther, 35(9), 469–474. https://doi.org/10.1089/jop.2019.0041
Woodward, David F., Jenny W. Wang, W Daniel Stamer, E. Lütjen-Drecoll, Achim H-P Krauss, and Carol B. Toris. “Antiglaucoma EP2 Agonists: A Long Road That Led Somewhere.J Ocul Pharmacol Ther 35, no. 9 (November 2019): 469–74. https://doi.org/10.1089/jop.2019.0041.
Woodward DF, Wang JW, Stamer WD, Lütjen-Drecoll E, Krauss AH-P, Toris CB. Antiglaucoma EP2 Agonists: A Long Road That Led Somewhere. J Ocul Pharmacol Ther. 2019 Nov;35(9):469–74.
Woodward, David F., et al. “Antiglaucoma EP2 Agonists: A Long Road That Led Somewhere.J Ocul Pharmacol Ther, vol. 35, no. 9, Nov. 2019, pp. 469–74. Pubmed, doi:10.1089/jop.2019.0041.
Woodward DF, Wang JW, Stamer WD, Lütjen-Drecoll E, Krauss AH-P, Toris CB. Antiglaucoma EP2 Agonists: A Long Road That Led Somewhere. J Ocul Pharmacol Ther. 2019 Nov;35(9):469–474.
Journal cover image

Published In

J Ocul Pharmacol Ther

DOI

EISSN

1557-7732

Publication Date

November 2019

Volume

35

Issue

9

Start / End Page

469 / 474

Location

United States

Related Subject Headings

  • Receptors, Prostaglandin E, EP2 Subtype
  • Ophthalmology & Optometry
  • Humans
  • Glaucoma
  • Drug Delivery Systems
  • Antihypertensive Agents
  • Animals
  • 3214 Pharmacology and pharmaceutical sciences
  • 3212 Ophthalmology and optometry
  • 1115 Pharmacology and Pharmaceutical Sciences