Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?
Publication
, Journal Article
Khasraw, M; Bell, D; Wheeler, H
Published in: J Clin Neurosci
June 2009
Temozolomide (TMZ) is an alkylating agent used in the management of gliomas. Although TMZ is generally safe and acute toxicity is well documented, there are limited data on long-term toxicities. We present three patients with glioma; all patients started on TMZ after having progressed following primary treatment. These patients have continued TMZ for 5 years, 7 years and 8 years respectively. So far they have had no serious side effects. We discuss these patients while raising the question of prolonged TMZ use.
Duke Scholars
Published In
J Clin Neurosci
DOI
ISSN
0967-5868
Publication Date
June 2009
Volume
16
Issue
6
Start / End Page
854 / 855
Location
Scotland
Related Subject Headings
- Treatment Outcome
- Time
- Temozolomide
- Retrospective Studies
- Radiotherapy
- Neurosurgical Procedures
- Neurology & Neurosurgery
- Neoplasm Recurrence, Local
- Middle Aged
- Male
Citation
APA
Chicago
ICMJE
MLA
NLM
Khasraw, M., Bell, D., & Wheeler, H. (2009). Long-term use of temozolomide: could you use temozolomide safely for life in gliomas? J Clin Neurosci, 16(6), 854–855. https://doi.org/10.1016/j.jocn.2008.09.005
Khasraw, Mustafa, David Bell, and Helen Wheeler. “Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?” J Clin Neurosci 16, no. 6 (June 2009): 854–55. https://doi.org/10.1016/j.jocn.2008.09.005.
Khasraw M, Bell D, Wheeler H. Long-term use of temozolomide: could you use temozolomide safely for life in gliomas? J Clin Neurosci. 2009 Jun;16(6):854–5.
Khasraw, Mustafa, et al. “Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?” J Clin Neurosci, vol. 16, no. 6, June 2009, pp. 854–55. Pubmed, doi:10.1016/j.jocn.2008.09.005.
Khasraw M, Bell D, Wheeler H. Long-term use of temozolomide: could you use temozolomide safely for life in gliomas? J Clin Neurosci. 2009 Jun;16(6):854–855.
Published In
J Clin Neurosci
DOI
ISSN
0967-5868
Publication Date
June 2009
Volume
16
Issue
6
Start / End Page
854 / 855
Location
Scotland
Related Subject Headings
- Treatment Outcome
- Time
- Temozolomide
- Retrospective Studies
- Radiotherapy
- Neurosurgical Procedures
- Neurology & Neurosurgery
- Neoplasm Recurrence, Local
- Middle Aged
- Male