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Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification.

Publication ,  Journal Article
Chen, Y; Wilson, JA; Petersen, SR; Luong, D; Sallam, S; Mao, J; Wesdemiotis, C; Becker, ML
Published in: Angewandte Chemie (International ed. in English)
September 2018

Three functional epoxides were copolymerized with maleic anhydride to yield degradable poly(propylene fumarate) analogues. The polymers were modified post-polymerization and post-printing with either click-type addition reactions or UV deprotection to either attach bioactive species or increase the hydrophilicity. Successful dye attachment, induced wettability, and improved cell spreading show the viability of these analogues in biomaterials applications.

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Published In

Angewandte Chemie (International ed. in English)

DOI

EISSN

1521-3773

ISSN

1433-7851

Publication Date

September 2018

Volume

57

Issue

39

Start / End Page

12759 / 12764

Related Subject Headings

  • Spectrophotometry
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Polypropylenes
  • Polymerization
  • Organic Chemistry
  • Microscopy, Fluorescence
  • Mice
  • Maleic Anhydrides
  • Fumarates
  • Epoxy Compounds
 

Citation

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Chen, Y., Wilson, J. A., Petersen, S. R., Luong, D., Sallam, S., Mao, J., … Becker, M. L. (2018). Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification. Angewandte Chemie (International Ed. in English), 57(39), 12759–12764. https://doi.org/10.1002/anie.201807419
Chen, Yusheng, James A. Wilson, Shannon R. Petersen, Derek Luong, Sahar Sallam, Jialin Mao, Chrys Wesdemiotis, and Matthew L. Becker. “Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification.Angewandte Chemie (International Ed. in English) 57, no. 39 (September 2018): 12759–64. https://doi.org/10.1002/anie.201807419.
Chen Y, Wilson JA, Petersen SR, Luong D, Sallam S, Mao J, et al. Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification. Angewandte Chemie (International ed in English). 2018 Sep;57(39):12759–64.
Chen, Yusheng, et al. “Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification.Angewandte Chemie (International Ed. in English), vol. 57, no. 39, Sept. 2018, pp. 12759–64. Epmc, doi:10.1002/anie.201807419.
Chen Y, Wilson JA, Petersen SR, Luong D, Sallam S, Mao J, Wesdemiotis C, Becker ML. Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification. Angewandte Chemie (International ed in English). 2018 Sep;57(39):12759–12764.
Journal cover image

Published In

Angewandte Chemie (International ed. in English)

DOI

EISSN

1521-3773

ISSN

1433-7851

Publication Date

September 2018

Volume

57

Issue

39

Start / End Page

12759 / 12764

Related Subject Headings

  • Spectrophotometry
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Polypropylenes
  • Polymerization
  • Organic Chemistry
  • Microscopy, Fluorescence
  • Mice
  • Maleic Anhydrides
  • Fumarates
  • Epoxy Compounds