Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis.
Publication
, Journal Article
Castano, M; Seo, KS; Kim, EH; Becker, ML; Puskas, JE
Published in: Macromolecular rapid communications
September 2013
Halo-ester-functionalized poly(ethylene glycol)s (PEGs) are successfully prepared by the transesterification of alkyl halo-esters with PEGs using Candida antarctica lipase B (CALB) as a biocatalyst under the solventless conditions. Transesterifications of chlorine, bromine, and iodine esters with tetraethylene glycol monobenzyl ether (BzTEG) are quantitative in less than 2.5 h. The transesterification of halo-esters with PEGs are complete in 4 h. (1) H and (13) C NMR spectroscopy with MALDI-ToF and ESI mass spectrometry confirm the structure and purity of the products. This method provides a convenient and "green" process to effectively produce halo-ester PEGs.
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Published In
Macromolecular rapid communications
DOI
EISSN
1521-3927
ISSN
1022-1336
Publication Date
September 2013
Volume
34
Issue
17
Start / End Page
1375 / 1380
Related Subject Headings
- Polymers
- Polyethylene Glycols
- Magnetic Resonance Spectroscopy
- Lipase
- Fungal Proteins
- Candida
- 40 Engineering
- 34 Chemical sciences
- 09 Engineering
- 03 Chemical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Castano, M., Seo, K. S., Kim, E. H., Becker, M. L., & Puskas, J. E. (2013). Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis. Macromolecular Rapid Communications, 34(17), 1375–1380. https://doi.org/10.1002/marc.201300430
Castano, Marcela, Kwang Su Seo, Eun Hye Kim, Matthew L. Becker, and Judit E. Puskas. “Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis.” Macromolecular Rapid Communications 34, no. 17 (September 2013): 1375–80. https://doi.org/10.1002/marc.201300430.
Castano M, Seo KS, Kim EH, Becker ML, Puskas JE. Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis. Macromolecular rapid communications. 2013 Sep;34(17):1375–80.
Castano, Marcela, et al. “Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis.” Macromolecular Rapid Communications, vol. 34, no. 17, Sept. 2013, pp. 1375–80. Epmc, doi:10.1002/marc.201300430.
Castano M, Seo KS, Kim EH, Becker ML, Puskas JE. Green polymer chemistry VIII: synthesis of halo-ester-functionalized poly(ethylene glycol)s via enzymatic catalysis. Macromolecular rapid communications. 2013 Sep;34(17):1375–1380.
Published In
Macromolecular rapid communications
DOI
EISSN
1521-3927
ISSN
1022-1336
Publication Date
September 2013
Volume
34
Issue
17
Start / End Page
1375 / 1380
Related Subject Headings
- Polymers
- Polyethylene Glycols
- Magnetic Resonance Spectroscopy
- Lipase
- Fungal Proteins
- Candida
- 40 Engineering
- 34 Chemical sciences
- 09 Engineering
- 03 Chemical Sciences