N-Acetylcysteine in the Management of Acute Liver Failure From Sickle Cell Hepatic Crisis.
Publication
, Journal Article
Zhang, X; Burroughs, S; Farooq, A; Bashir, MR; Muir, AJ; Patel, YA
Published in: ACG Case Rep J
August 2019
N-acetylcysteine (NAC) has been well studied in the treatment of acetaminophen-induced and select non-acetaminophen-induced liver failure. However, its role in the management of sickle cell hepatic crisis resulting in acute liver failure (ALF) is unknown. We describe and discuss the novel and beneficial use of NAC in a 25-year-old man with ALF due to sickle cell hepatic crisis. We further review ALF in sickle cell disease and NAC in the treatment of non-acetaminophen-induced liver failure. Our case highlights the promising role of NAC in sickle cell-related liver injury.
Duke Scholars
Published In
ACG Case Rep J
DOI
ISSN
2326-3253
Publication Date
August 2019
Volume
6
Issue
8
Start / End Page
e00161
Location
United States
Citation
APA
Chicago
ICMJE
MLA
NLM
Zhang, X., Burroughs, S., Farooq, A., Bashir, M. R., Muir, A. J., & Patel, Y. A. (2019). N-Acetylcysteine in the Management of Acute Liver Failure From Sickle Cell Hepatic Crisis. ACG Case Rep J, 6(8), e00161. https://doi.org/10.14309/crj.0000000000000161
Zhang, Xiaojie, Sarah Burroughs, Ahmad Farooq, Mustafa R. Bashir, Andrew J. Muir, and Yuval A. Patel. “N-Acetylcysteine in the Management of Acute Liver Failure From Sickle Cell Hepatic Crisis.” ACG Case Rep J 6, no. 8 (August 2019): e00161. https://doi.org/10.14309/crj.0000000000000161.
Zhang X, Burroughs S, Farooq A, Bashir MR, Muir AJ, Patel YA. N-Acetylcysteine in the Management of Acute Liver Failure From Sickle Cell Hepatic Crisis. ACG Case Rep J. 2019 Aug;6(8):e00161.
Zhang, Xiaojie, et al. “N-Acetylcysteine in the Management of Acute Liver Failure From Sickle Cell Hepatic Crisis.” ACG Case Rep J, vol. 6, no. 8, Aug. 2019, p. e00161. Pubmed, doi:10.14309/crj.0000000000000161.
Zhang X, Burroughs S, Farooq A, Bashir MR, Muir AJ, Patel YA. N-Acetylcysteine in the Management of Acute Liver Failure From Sickle Cell Hepatic Crisis. ACG Case Rep J. 2019 Aug;6(8):e00161.
Published In
ACG Case Rep J
DOI
ISSN
2326-3253
Publication Date
August 2019
Volume
6
Issue
8
Start / End Page
e00161
Location
United States