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Failure of viral shells.

Publication ,  Journal Article
Klug, WS; Bruinsma, RF; Michel, J-P; Knobler, CM; Ivanovska, IL; Schmidt, CF; Wuite, GJL
Published in: Physical review letters
December 2006

We report a combined theoretical and experimental study of the structural failure of viral shells under mechanical stress. We find that discontinuities in the force-indentation curve associated with failure should appear when the so-called Föppl-von Kármán (FvK) number exceeds a critical value. A nanoindentation study of a viral shell subject to a soft-mode instability, where the stiffness of the shell decreases with increasing pH, confirms the predicted onset of failure as a function of the FvK number.

Duke Scholars

Published In

Physical review letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

December 2006

Volume

97

Issue

22

Start / End Page

228101

Related Subject Headings

  • Stress, Mechanical
  • Models, Biological
  • Microscopy, Atomic Force
  • Hydrogen-Ion Concentration
  • General Physics
  • Elasticity
  • Capsid
  • Bromovirus
  • Biophysics
  • Biophysical Phenomena
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Klug, W. S., Bruinsma, R. F., Michel, J.-P., Knobler, C. M., Ivanovska, I. L., Schmidt, C. F., & Wuite, G. J. L. (2006). Failure of viral shells. Physical Review Letters, 97(22), 228101. https://doi.org/10.1103/physrevlett.97.228101
Klug, William S., Robijn F. Bruinsma, Jean-Philippe Michel, Charles M. Knobler, Irena L. Ivanovska, Christoph F. Schmidt, and Gijs J. L. Wuite. “Failure of viral shells.Physical Review Letters 97, no. 22 (December 2006): 228101. https://doi.org/10.1103/physrevlett.97.228101.
Klug WS, Bruinsma RF, Michel J-P, Knobler CM, Ivanovska IL, Schmidt CF, et al. Failure of viral shells. Physical review letters. 2006 Dec;97(22):228101.
Klug, William S., et al. “Failure of viral shells.Physical Review Letters, vol. 97, no. 22, Dec. 2006, p. 228101. Epmc, doi:10.1103/physrevlett.97.228101.
Klug WS, Bruinsma RF, Michel J-P, Knobler CM, Ivanovska IL, Schmidt CF, Wuite GJL. Failure of viral shells. Physical review letters. 2006 Dec;97(22):228101.

Published In

Physical review letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

December 2006

Volume

97

Issue

22

Start / End Page

228101

Related Subject Headings

  • Stress, Mechanical
  • Models, Biological
  • Microscopy, Atomic Force
  • Hydrogen-Ion Concentration
  • General Physics
  • Elasticity
  • Capsid
  • Bromovirus
  • Biophysics
  • Biophysical Phenomena