Skip to main content

Scale-dependent nonaffine elasticity of semiflexible polymer networks

Publication ,  Journal Article
Atakhorrami, M; Koenderink, GH; Palierne, JF; Mackintosh, FC; Schmidt, CF
Published in: Physical Review Letters
February 24, 2014

The cytoskeleton of eukaryotic cells provides mechanical support and governs intracellular transport. These functions rely on the complex mechanical properties of networks of semiflexible protein filaments. We study the impact of local network deformations on the scale-dependent mobility of probe particles in entangled networks of actin filaments using high-bandwidth microrheology. We find that micron-sized particles in these networks experience two opposing noncontinuum elastic effects: entropic depletion reduces the effective network rigidity, while local nonaffine deformations of the network substantially enhance the rigidity at low frequencies, eventually leading to a size-independent response and strong violation of the generalized Stokes formula. We show that a simple model of lateral bending of filaments embedded in a viscoelastic background leads to an intermediate scaling regime for the apparent elastic modulus G′(ω)∼ω9/16, closely matching the experiments. These results demonstrate that nonaffine bending deformations can be dominant for the mobility of objects of the size of vesicles and organelles in the cell. © 2014 American Physical Society.

Duke Scholars

Published In

Physical Review Letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

February 24, 2014

Volume

112

Issue

8

Related Subject Headings

  • General Physics
  • 51 Physical sciences
  • 49 Mathematical sciences
  • 40 Engineering
  • 09 Engineering
  • 02 Physical Sciences
  • 01 Mathematical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Atakhorrami, M., Koenderink, G. H., Palierne, J. F., Mackintosh, F. C., & Schmidt, C. F. (2014). Scale-dependent nonaffine elasticity of semiflexible polymer networks. Physical Review Letters, 112(8). https://doi.org/10.1103/PhysRevLett.112.088101
Atakhorrami, M., G. H. Koenderink, J. F. Palierne, F. C. Mackintosh, and C. F. Schmidt. “Scale-dependent nonaffine elasticity of semiflexible polymer networks.” Physical Review Letters 112, no. 8 (February 24, 2014). https://doi.org/10.1103/PhysRevLett.112.088101.
Atakhorrami M, Koenderink GH, Palierne JF, Mackintosh FC, Schmidt CF. Scale-dependent nonaffine elasticity of semiflexible polymer networks. Physical Review Letters. 2014 Feb 24;112(8).
Atakhorrami, M., et al. “Scale-dependent nonaffine elasticity of semiflexible polymer networks.” Physical Review Letters, vol. 112, no. 8, Feb. 2014. Scopus, doi:10.1103/PhysRevLett.112.088101.
Atakhorrami M, Koenderink GH, Palierne JF, Mackintosh FC, Schmidt CF. Scale-dependent nonaffine elasticity of semiflexible polymer networks. Physical Review Letters. 2014 Feb 24;112(8).

Published In

Physical Review Letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

February 24, 2014

Volume

112

Issue

8

Related Subject Headings

  • General Physics
  • 51 Physical sciences
  • 49 Mathematical sciences
  • 40 Engineering
  • 09 Engineering
  • 02 Physical Sciences
  • 01 Mathematical Sciences