Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis.
Publication
, Journal Article
Donn, RP; Farhan, A; Stevans, A; Ramanan, A; Ollier, WER; Thomson, W; British Paediatric Rheumatology Study Group
Published in: Rheumatology (Oxford)
August 2002
OBJECTIVE: To investigate the involvement of neuroendocrine candidate genes in the aetiopathogenesis of juvenile idiopathic arthritis (JIA). METHODS: Single-nucleotide polymorphisms and intragenic microsatellite markers within five neuroendocrine candidate genes (CRH, CBG, CYP19, ESR1, PRL) were investigated in 463 clinically characterized UK Caucasian JIA patients and a panel of 276 unrelated, healthy UK Caucasian controls. RESULTS: None of the polymorphisms investigated showed any statistically significant associations with JIA. CONCLUSIONS: The lack of association with polymorphisms of these neuroendocrine genes suggests that they are not involved in susceptibility to JIA.
Duke Scholars
Published In
Rheumatology (Oxford)
DOI
ISSN
1462-0324
Publication Date
August 2002
Volume
41
Issue
8
Start / End Page
930 / 936
Location
England
Related Subject Headings
- White People
- United Kingdom
- Transcortin
- Reference Values
- Receptors, Estrogen
- Prolactin
- Polymorphism, Genetic
- Pituitary-Adrenal System
- Microsatellite Repeats
- Male
Citation
APA
Chicago
ICMJE
MLA
NLM
Donn, R. P., Farhan, A., Stevans, A., Ramanan, A., Ollier, W. E. R., Thomson, W., & British Paediatric Rheumatology Study Group. (2002). Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. Rheumatology (Oxford), 41(8), 930–936. https://doi.org/10.1093/rheumatology/41.8.930
Donn, R. P., A. Farhan, A. Stevans, A. Ramanan, W. E. R. Ollier, W. Thomson, and British Paediatric Rheumatology Study Group. “Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis.” Rheumatology (Oxford) 41, no. 8 (August 2002): 930–36. https://doi.org/10.1093/rheumatology/41.8.930.
Donn RP, Farhan A, Stevans A, Ramanan A, Ollier WER, Thomson W, et al. Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. Rheumatology (Oxford). 2002 Aug;41(8):930–6.
Donn, R. P., et al. “Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis.” Rheumatology (Oxford), vol. 41, no. 8, Aug. 2002, pp. 930–36. Pubmed, doi:10.1093/rheumatology/41.8.930.
Donn RP, Farhan A, Stevans A, Ramanan A, Ollier WER, Thomson W, British Paediatric Rheumatology Study Group. Neuroendocrine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. Rheumatology (Oxford). 2002 Aug;41(8):930–936.
Published In
Rheumatology (Oxford)
DOI
ISSN
1462-0324
Publication Date
August 2002
Volume
41
Issue
8
Start / End Page
930 / 936
Location
England
Related Subject Headings
- White People
- United Kingdom
- Transcortin
- Reference Values
- Receptors, Estrogen
- Prolactin
- Polymorphism, Genetic
- Pituitary-Adrenal System
- Microsatellite Repeats
- Male