Encyclopedia of Cancer
Helicobacter Pylori-mediated carcinogenesis
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Varga, MG; Epplein, M
January 1, 2018
Helicobacter pylori is the most successful bacterial pathogen worldwide, coevolving with humans for millennia and currently infecting over 50% of the global populous. It is a Gram-negative, spiral-shaped organism that can evade the immune response for the lifetime of its host. The identification of H. pylori as an etiological agent of gastric adenocarcinoma led to its classification as a class I carcinogen. Improved hygiene and targeted eradication with antibiotic therapy have been efficacious in reducing the incidence of gastric cancer, but the opportunity remains to further reduce the burden of H. pylori-associated disease through testing and treatment of high-risk populations.
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Varga, M. G., & Epplein, M. (2018). Helicobacter Pylori-mediated carcinogenesis. In Encyclopedia of Cancer (pp. 187–197). https://doi.org/10.1016/B978-0-12-801238-3.65172-3
Varga, M. G., and M. Epplein. “Helicobacter Pylori-mediated carcinogenesis.” In Encyclopedia of Cancer, 187–97, 2018. https://doi.org/10.1016/B978-0-12-801238-3.65172-3.
Varga MG, Epplein M. Helicobacter Pylori-mediated carcinogenesis. In: Encyclopedia of Cancer. 2018. p. 187–97.
Varga, M. G., and M. Epplein. “Helicobacter Pylori-mediated carcinogenesis.” Encyclopedia of Cancer, 2018, pp. 187–97. Scopus, doi:10.1016/B978-0-12-801238-3.65172-3.
Varga MG, Epplein M. Helicobacter Pylori-mediated carcinogenesis. Encyclopedia of Cancer. 2018. p. 187–197.