Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry.
Publication
, Journal Article
Umuhire Juru, A; Cai, Z; Jan, A; Hargrove, AE
Published in: Chemical communications (Cambridge, England)
March 2020
This study establishes the applicability of imine-based dynamic combinatorial chemistry to discover non-covalent ligands for RNA targets. We elucidate properties underlying the reactivity of arylamines and demonstrate target-guided amplification of tight binders in an amiloride-based dynamic library.
Duke Scholars
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Published In
Chemical communications (Cambridge, England)
DOI
EISSN
1364-548X
ISSN
1359-7345
Publication Date
March 2020
Volume
56
Issue
24
Start / End Page
3555 / 3558
Related Subject Headings
- RNA
- Organic Chemistry
- Ligands
- Imines
- HIV Long Terminal Repeat
- Genes, env
- Combinatorial Chemistry Techniques
- Amines
- 40 Engineering
- 34 Chemical sciences
Citation
APA
Chicago
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MLA
NLM
Umuhire Juru, A., Cai, Z., Jan, A., & Hargrove, A. E. (2020). Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry. Chemical Communications (Cambridge, England), 56(24), 3555–3558. https://doi.org/10.1039/d0cc00266f
Umuhire Juru, Aline, Zhengguo Cai, Adina Jan, and Amanda E. Hargrove. “Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry.” Chemical Communications (Cambridge, England) 56, no. 24 (March 2020): 3555–58. https://doi.org/10.1039/d0cc00266f.
Umuhire Juru A, Cai Z, Jan A, Hargrove AE. Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry. Chemical communications (Cambridge, England). 2020 Mar;56(24):3555–8.
Umuhire Juru, Aline, et al. “Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry.” Chemical Communications (Cambridge, England), vol. 56, no. 24, Mar. 2020, pp. 3555–58. Epmc, doi:10.1039/d0cc00266f.
Umuhire Juru A, Cai Z, Jan A, Hargrove AE. Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry. Chemical communications (Cambridge, England). 2020 Mar;56(24):3555–3558.
Published In
Chemical communications (Cambridge, England)
DOI
EISSN
1364-548X
ISSN
1359-7345
Publication Date
March 2020
Volume
56
Issue
24
Start / End Page
3555 / 3558
Related Subject Headings
- RNA
- Organic Chemistry
- Ligands
- Imines
- HIV Long Terminal Repeat
- Genes, env
- Combinatorial Chemistry Techniques
- Amines
- 40 Engineering
- 34 Chemical sciences